Evidence map›Paper›PMID 32309637›Full record

ArticleJournal of psychiatry and brain science2020

Progress Report on EMBED: A Pragmatic Trial of User-Centered Clinical Decision Support to Implement EMergency Department-Initiated BuprenorphinE for Opioid Use Disorder.

Edward R Melnick, Bidisha Nath, Osama M Ahmed, Cynthia Brandt, David Chartash, James D Dziura, Erik P Hess, Wesley C Holland, Jason A Hoppe, Molly M Jeffery and 18 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Journal of psychiatry and brain science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03658642 (Pragmatic Trial of User-centered Clinical Decision Support to Implement EMergency Department-initiated BuprenorphinE for Opioid Use Disorder), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03658642 nacompletednot on this map

Pragmatic Trial of User-centered Clinical Decision Support to Implement EMergency Department-initiated BuprenorphinE for Opioid Use Disorder

TypeinterventionalSponsorYale UniversityRan2019 to 2021Enrolled5,047ConditionsClinical Decision Support, Buprenorphine, Opioid-use DisorderArmsClinical Decision Support (CDS)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Racial and ethnic disparities in emergency department-initiated buprenorphine across five health care systems.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2023
    Article
  3. Article
  4. Article
  5. Pragmatic clinical trial design in emergency medicine: Study considerations and design types.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2022
    Article
  6. Article
  7. Redesign of Opioid Use Disorder Screening and Treatment in the ED.NEJM catalyst innovations in care delivery · 2022
    Article
  8. "This is part of emergency medicine now": A qualitative assessment of emergency clinicians' facilitators of and barriers to initiating buprenorphine.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 4 institutions in 1 country.

Edward R MelnickDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, CT 06519, USA.
Bidisha NathDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, CT 06519, USA.
Osama M AhmedYale University School of Medicine, New Haven, CT 06510, USA.
Cynthia BrandtDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, CT 06519, USA.
David ChartashYale Center for Medical Informatics, Yale University School of Medicine, New Haven, CT 06511, USA.
James D DziuraYale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT 06520, USA.
Erik P HessDepartment of Emergency Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35233, USA.
Wesley C HollandYale University School of Medicine, New Haven, CT 06510, USA.
Jason A HoppeDepartment of Emergency Medicine, University of Colorado, Aurora, CO 80045, USA.
Molly M JefferyDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Liliya KatsovichYale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT 06520, USA.
Fangyong LiYale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT 06520, USA.
Charles C LuYale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT 06520, USA.
Kaitlin MaciejewskiYale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT 06520, USA.
Matthew MaleskaThe Patient Revolution, New Haven, CT 06511, USA.
Jodi A MaoYale University School of Medicine, New Haven, CT 06510, USA.
Shara MartelDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, CT 06519, USA.
Sean MichaelDepartment of Emergency Medicine, University of Colorado, Aurora, CO 80045, USA.
Hyung PaekInformation Technology Services, Yale New-Haven Health, New Haven, CT 06519, USA.
Mehul D PatelDepartment of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Timothy F Platts-MillsDepartment of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Haseena RajeevanYale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT 06520, USA.
Jessica M RayDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, CT 06519, USA.
Rachel M SkainsDepartment of Emergency Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35233, USA.
William E SoaresDepartment of Emergency Medicine, University of Massachusetts Medical School-Baystate, Baystate, MA 01199, USA.
Ashley DeutschDepartment of Emergency Medicine, University of Massachusetts Medical School-Baystate, Baystate, MA 01199, USA.
Yauheni SoladInformation Technology Services, Yale New-Haven Health, New Haven, CT 06519, USA.
Gail D'OnofrioDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, CT 06519, USA.
Yale University · USMayo Clinic in Arizona · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
MEDICAL INFORMATICS RESEARCH TRAINING AT YALET15LM007056 · NLM · YALE UNIVERSITY · PI Mark Bender Gerstein, LUCILA OHNO-MACHADO · 1987 to 2026
$22.2M
NIH Health Care Systems Research Collaboratory-Coordinating Center (U24)U24AT009676 · NCCIH · DUKE UNIVERSITY · PI LESLEY H CURTIS, Adrian Hernandez · 2017 to 2026
$21.5M
EMBED: Pragmatic trial of user-centered clinical decision support to implement EMergency department-initiated BuprenorphinE for opioid use DisorderUH3DA047003 · NIDA · YALE UNIVERSITY · PI D'ONOFRIO, GAIL, MELNICK, EDWARD ROBERT · 2019 to 2022
$7.2M
Short-Term Reserch Training: Students in Health SchoolsT35HL007649 · NHLBI · YALE UNIVERSITY · PI Sarwat I Chaudhry, Erica L Herzog · 1987 to 2026
$5.7M
EMBED: Pragmatic trial of user-centered clinical decision support to implement EMergency department-initiated BuprenorphinE for opioid use DisorderUG3DA047003 · NIDA · YALE UNIVERSITY · PI D'ONOFRIO, GAIL, MELNICK, EDWARD ROBERT · 2018 to 2018
$819k
NCATS NIH HHS UL1 TR001863NCCIH NIH HHS U24 AT009676NHLBI NIH HHS T35 HL007649NIDA NIH HHS UG3 DA047003NIDA NIH HHS UH3 DA047003NLM NIH HHS T15 LM007056
6 · The paper itself

Abstract

Buprenorphine (BUP) can safely and effectively reduce craving, overdose, and mortality rates in people with opioid use disorder (OUD). However, adoption of ED-initiation of BUP has been slow partly due to physician perception this practice is too complex and disruptive. We report progress of the ongoing EMBED (

trial registrationClinicaltrials.gov # NCT03658642.

Indexed as

buprenorphineclinical decision support systemselectronic health recordshealth informaticshealth information technologymedication for opioid use disorder (MOUD)opioid-related disordersopioid use disorderquality improvementuser-centered design

Identifiers

PMID32309637
PMCPMC7164817
OpenAlexW3006956012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.