Evidence map›Paper›PMID 32309475›Full record

ArticleACG case reports journal2019

Challenges in Management of Autoimmune Hepatitis With Concurrent Graves Thyrotoxicosis.

Ngan Nguyen, Yala Kirthi Reddy, Nidhi Jain, Vanisha Patel, Deirdre James, Bobbak Sistani, Helmut Steinberg

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ngan NguyenDepartment of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN.
Yala Kirthi ReddyDepartment of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN.
Nidhi JainDepartment of Endocrinology, University of Tennessee Health Science Center, Memphis, TN.
Vanisha PatelUniversity of Tennessee Health Science Center, Memphis, TN.
Deirdre JamesDepartment of Endocrinology, University of Tennessee Health Science Center, Memphis, TN.
Bobbak SistaniDepartment of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN.
Helmut SteinbergDepartment of Endocrinology, University of Tennessee Health Science Center, Memphis, TN.
University of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of concurrent Graves thyrotoxicosis and autoimmune hepatitis (AIH) can be challenging. We present a 37-year-old woman with a recent diagnosis of Graves disease and acute liver injury. Laboratory workup was concerning for AIH. Liver biopsy showed plasma cell infiltration and interface hepatitis consistent with AIH, and treatment with methylprednisolone was initiated. Azathioprine was started after thiopurine methyltransferase testing, and prednisone was tapered down. Thionamide use was contraindicated, so clinical euthyroidism was achieved with the use of cholestyramine and glucocorticoids. Our case highlights the complexities of management when patients are affected by 2 concurrent illnesses.

Identifiers

PMID32309475
PMCPMC7145210
OpenAlexW2993090132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.