Evidence map›Paper›PMID 32309376›Full record

ArticleAnnals of translational medicine2020

Zhen Zhu, Yanfeng Jiang, Mei Cui, Yingzhe Wang, Shuyuan Li, Kelin Xu, Kexun Zhang, Chengkai Zhu, Wanghong Xu, Li Jin and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Zhen ZhuDepartment of Epidemiology, School of Public Health, and the Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200438, China.
Yanfeng JiangState Key Laboratory of Genetic Engineering, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Mei CuiDepartment of Neurology, Huashan Hospital, Fudan University, Shanghai 200030, China.
Yingzhe WangDepartment of Neurology, Huashan Hospital, Fudan University, Shanghai 200030, China.
Shuyuan LiInternational Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China.
Kelin XuState Key Laboratory of Genetic Engineering, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Kexun ZhangDepartment of Epidemiology, School of Public Health, and the Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200438, China.
Chengkai ZhuState Key Laboratory of Genetic Engineering, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Wanghong XuDepartment of Epidemiology, School of Public Health, and the Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200438, China.
Li JinState Key Laboratory of Genetic Engineering, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Weimin YeState Key Laboratory of Genetic Engineering, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Chen SuoDepartment of Epidemiology, School of Public Health, and the Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200438, China.
Xingdong ChenState Key Laboratory of Genetic Engineering, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Fudan University · CNHuashan Hospital · CNTaizhou University · CNKarolinska Institutet · SEShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral microbleeds (CMBs) are more prevalent in Asian populations, and have been associated with increased risk of stroke, dementia and mortality. So far, risk factors for CMBs other than hypertension were merely known. Previous studies have shown that polymorphisms at aldehyde dehydrogenase 2 (

methodsUsing bio-specimen and data collected at baseline survey of the population-based Taizhou Imaging Study (TIS) (phase I), we genotyped the single nucleotide polymorphisms (SNPs) at

resultsCMBs were present in 103 individuals (18.8%). Forty-one point three percent participants were with

conclusionsThe results suggest that Han Chinese with

Indexed as

aldehyde dehydrogenase 2 (ALDH2)brain magnetic resonance imaging (brain MRI)Cerebral microbleeds (CMBs)genetic association study

Identifiers

PMID32309376
PMCPMC7154495
OpenAlexW3004079707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.