Evidence map›Paper›PMID 32309358›Full record

ArticleAnnals of translational medicine2020

An intronic polymorphism of

Zijie Wang, Hengcheng Zhang, Haiwei Yang, Ming Zheng, Miao Guo, Hao Chen, Li Sun, Zhijian Han, Jun Tao, Xiaobing Ju and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Association Between aFrontiers in genetics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zijie WangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Hengcheng ZhangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Haiwei YangDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Ming ZhengDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Miao GuoResearch Division of Clinical Pharmacology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Hao ChenDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Li SunDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Zhijian HanDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Jun TaoDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Xiaobing JuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Ruoyun TanDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Ji-Fu WeiResearch Division of Clinical Pharmacology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Min GuDepartment of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Nanjing Medical University · CNJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to explore the influence of single nucleotide polymorphisms (SNPs) in

methodsBlood samples from 131 subjects with stable allograft function (STA) and 69 with BPAR episodes were collected and analyzed using target sequencing (TS) with an established panel. Odds ratios (OR) and 95% confidence intervals (95% CIs) were calculated for logistic regression models adjusted for confounding factors. Pathological changes were extracted and the relationship with tagger SNPs was calculated. Moreover, the CCK-8 assay was performed to explore the proliferation of T lymphocytes, and PCR, Western blotting and enzyme-linked immunosorbent assay were applied to identify the effect of mutant on the activation of T cells.

resultsHigh-quality readouts were obtained for 55

conclusionsWe reported the crucial association of

Indexed as

biopsy-proven acute rejection (BPAR)kidney transplantationNFATC1single nucleotide polymorphisms (SNPs)

Identifiers

PMID32309358
PMCPMC7154465
OpenAlexW3005256040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.