Evidence map›Paper›PMID 32309135›Full record

ReviewJournal of orthopaedic translation2020

Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version).

Dewei Zhao, Feng Zhang, Benjie Wang, Baoyi Liu, Lu Li, Shin-Yoon Kim, Stuart B Goodman, Philippe Hernigou, Quanjun Cui, William C Lineaweaver and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of orthopaedic translation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 273 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
273citing papers in PubMed, 16 pooled it
37.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

273 citing papers in PubMed, 16 syntheses or guidelines pooled it, 431 citations in OpenAlex.

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  3. Extracorporeal shock wave therapy (ESWT) for treatment of osteonecrosis of the femoral head: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
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213 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 6 countries.

Dewei ZhaoDepartment of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, PR China.
Feng ZhangJMS Burn and Reconstructive Center, Jackson, MS, USA.
Benjie WangDepartment of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, PR China.
Baoyi LiuDepartment of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, PR China.
Lu LiDepartment of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, PR China.
Shin-Yoon KimDepartment of Orthopaedic Surgery, Kyungpook National University Hospital, Daegu, South Korea.
Stuart B GoodmanDepartment of Orthopaedic Surgery and (by Courtesy) Bioengineering, Stanford University Medical Center Outpatient Center, Redwood City, CA, 94063, USA.
Philippe HernigouDepartment of Orthopaedic Surgery, University Paris East (UPEC), Hôpital Henri Mondor, Creteil, France.
Quanjun CuiDepartment of Orthopaedic Surgery, University of Virginia School of Medicine, Virginia, 22903, USA.
William C LineaweaverJMS Burn and Reconstructive Center, Jackson, MS, USA.
Jiake XuSchool of Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia, 6009, Australia.
Wolf R DrescherDepartment of Orthopaedic Surgery of the Lower Limb and Arthroplasty, Rummelsberg Hospital, D-90592, Schwarzenbruck, Germany.
Ling QinMusculoskeletal Research Laboratory, Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, PR China.
Affiliated Zhongshan Hospital of Dalian University · CNJackson Memorial Hospital · USChinese University of Hong Kong · HKKyungpook National University Hospital · KRStanford Medicine · USThe University of Western Australia · AUUniversité Paris-Est Créteil · FRUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteonecrosis of the femoral head (ONFH) is a common and refractory disease in orthopaedic clinics. The number of patients with ONFH is increasing worldwide every year. There are an estimated 8.12 million patients with nontraumatic osteonecrosis in China alone. Treatment of nontraumatic osteonecrosis has always been a clinical challenge for orthopaedic surgeons. To further standardize diagnosis and treatment of ONFH, these guidelines provide not only basic diagnosis, treatment, and evaluation systems for ONFH but also expert advice and standards in many aspects, including epidemiology, aetiology, diagnostic criteria, pathological staging, prevention and treatment options, and postoperative rehabilitation. The aetiological factors of ONFH can currently be divided into two major categories: traumatic and nontraumatic; however, the specific pathological mechanism of ONFH is not completely clear. Currently, the staging system of ONFH formulated by the Association Research Circulation Osseous is widely used in clinical practice. Based on the changes in the intraosseous blood supply at different stages, the corresponding nonsurgical and surgical treatments are recommended, and when there are risk factors for possible ONFH, certain preventive measures to avoid the occurrence of osteonecrosis are recommended. These guidelines provide brief classification criteria and treatment regimen for osteonecrosis. Specification of the aetiology, treatment plan based on comprehensive consideration of the different stages of osteonecrosis, hip function, age, and occupation of the patients are important steps in diagnosis and developing treatment strategies. TRANSLATIONAL POTENTIAL OF THIS ARTICLE: New advances in the epidemiology, etiology, pathophysiology, imaging, diagnosis and treatment of ONFH have been renewed in this revision. This guideline can be used for reference by orthopedic professionals and researchers, and for standardized diagnosis and treatment management under the clinical guidance, which is conducive to the prevention, treatment and further research of ONFH, improving the diagnosis and treatment level, making patients' symptoms under good control, and improving their quality of life.

Indexed as

ARCO, Association Research Circulation OsseousBMES, Bone marrow oedema syndromeCT, Computed tomographyDiagnosisDSA, Digital subtraction angiographyGuidelineMRI, Magnetic resonance imagingONFH, Osteonecrosis of the femoral headOsteonecrosis of the femoral head (ONFH)PET, Positron emission tomographyRHS, Reconstruction Hip ScoresSPECT, Single-photon emission computed tomographyT1WI, T1-weighted imagesTreatment

Identifiers

PMID32309135
PMCPMC7152793
OpenAlexW2999292999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.