Evidence map›Paper›PMID 32309041›Full record

ReviewJournal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B2020

Polyphosphazene polymers: The next generation of biomaterials for regenerative engineering and therapeutic drug delivery.

Kenneth S Ogueri, Kennedy S Ogueri, Harry R Allcock, Cato T Laurencin

Abstract readReview
In one paragraph

Review in Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Classes of Stem Cells: From Biology to Engineering.Regenerative engineering and translational medicine · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
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  11. Article
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  14. Review
  15. Article
  16. Biomedical applications of polyphosphazenes.Medical devices & sensors · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kennedy S OgueriDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802.ORCID 0000-0002-3847-8988
Harry R AllcockDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802.ORCID 0000-0002-8822-3457

Funding

Regenerative Engineering of Complex Musculoskeletal Tissues and JointsDP1AR068147 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LAURENCIN, CATO T. · 2014 to 2018
$4.1M
NIAMS NIH HHS DP1 AR068147
6 · The paper itself

Abstract

The demand for new biomaterials in several biomedical applications, such as regenerative engineering and drug delivery, has increased over the past two decades due to emerging technological advances in biomedicine. Degradable polymeric biomaterials continue to play a significant role as scaffolding materials and drug devices. Polyphosphazene platform is a subject of broad interest, as it presents an avenue for attaining versatile polymeric materials with excellent structure and property tunability, and high functional diversity. Macromolecular substitution enables the facile attachment of different organic groups and drug molecules to the polyphosphazene backbone for the development of a broad class of materials. These materials are more biocompatible than traditional biomaterials, mixable with other clinically relevant polymers to obtain new materials and exhibit unique erosion with near-neutral degradation products. Hence, polyphosphazene represents the next generation of biomaterials. In this review, the authors systematically discuss the synthetic design, structure-property relationships, and the promising potentials of polyphosphazenes in regenerative engineering and drug delivery.

Identifiers

PMID32309041
PMCPMC7156271

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.