Evidence map›Paper›PMID 32308992›Full record

ArticleInternational journal of Alzheimer's disease2020

Gervason Apiri Moriasi, Anthony Muriithi Ireri, Mathew Piero Ngugi

Abstract read
In one paragraph

Article in International journal of Alzheimer's disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Phytochemical Screening, Toxic Effects, and Antimicrobial Activity Studies ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  8. Article
  9. Evaluation of Uterotonic Activity, Acute Oral Toxicity, and Phytochemical Composition ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  10. Heliyon · 2021
    Article
  11. Evaluation of the Antimicrobial Effect of the Extracts of the Pods ofAdvances in pharmacological and pharmaceutical sciences · 2021
    Article
  12. Article
  13. Article
  14. Cognitive-Enhancing,Biochemistry research international · 2020
    Article
  15. In Vitro Antioxidant Activities of Methanolic Extracts ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gervason Apiri MoriasiDepartment of Biochemistry, Microbiology and Biotechnology, Kenyatta University, P.O BOX 43844-00100 Nairobi, Kenya.ORCID https://orcid.org/0000-0001-5604-9987
Anthony Muriithi IreriDepartment of Educational Psychology, Kenyatta University, P.O BOX 43844-00100 Nairobi, Kenya.
Mathew Piero NgugiDepartment of Biochemistry, Microbiology and Biotechnology, Kenyatta University, P.O BOX 43844-00100 Nairobi, Kenya.ORCID https://orcid.org/0000-0002-0226-9092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment (CI) is among the leading causes of disability in humans. It is estimated that over 35.6 million people are suffering from Alzheimer's disease- (AD-) associated cognitive deficits globally with these statistics projected to rise over 115.4 million by the year 2050. There is no specific etiology for this cognitive impairment; however, various contributing factors including advancing age (>60 years old), oxidative stress, cerebral injuries, infections, neurologic disorders, and cancer have been implicated. Despite various attempts to manage CI, no curative medicines are yet available. The current drugs used to manage symptoms of AD-associated CI including Donepezil and Rivastigmine among others are only palliative rather than therapeutic. Furthermore, these agents have been associated with undesirable side effects. This calls for alternative and complementary approaches aimed at either preventing or reverting AD-related CI in a curative way without causing adverse events. It is estimated that over 80% of the world's population utilize herbal medicines for basic healthcare as it is considered safe, affordable, and easily accessible as opposed to conventional healthcare. Various parts of

Identifiers

PMID32308992
PMCPMC7128055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.