Evidence map›Paper›PMID 32308921›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2019

Relation Extraction from Clinical Narratives Using Pre-trained Language Models.

Qiang Wei, Zongcheng Ji, Yuqi Si, Jingcheng Du, Jingqi Wang, Firat Tiryaki, Stephen Wu, Cui Tao, Kirk Roberts, Hua Xu

Open access · greenAbstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 56 citations in OpenAlex.

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  4. AI assistance in tumor multidisciplinary teams.ESMO real world data and digital oncology · 2026
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  6. LitTx: A New Treatment Relation Extraction Dataset.LREC ... International Conference on Language Resources & Evaluation : [proceedings]. International Conference on Language Resources & Evaluation · 2026
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  7. Efficient extraction of medication information from clinical notes: an evaluation in 2 languages.Journal of the American Medical Informatics Association : JAMIA · 2025
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  10. Enhancing Cross-Domain Generalizability in Social Determinants of Health Extraction with Prompt-Tuning Large Language Models.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025
    Article
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  12. Transformers and large language models in healthcare: A review.Artificial intelligence in medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Qiang WeiSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Zongcheng JiSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Yuqi SiSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Jingcheng DuSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Jingqi WangSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Firat TiryakiSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Stephen WuSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Cui TaoSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Kirk RobertsSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Hua XuSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
The University of Texas Health Science Center at Houston · US

Funding

Open Health Natural Language Processing CollaboratoryU01TR002062 · NCATS · MAYO CLINIC ROCHESTER · PI JIANG, XIAOQIAN, LIU, HONGFANG · 2017 to 2021
$7.6M
Advancing Cancer Pharmacoepidemiology Research Through EHRs and InformaticsU24CA194215 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAO, CUI, YANG, PING · 2016 to 2020
$3.3M
Real-time Disambiguation of Abbreviations in Clinical NotesR01LM010681 · NLM · VANDERBILT UNIVERSITY · PI XU, HUA · 2010 to 2017
$3.1M
Natural Language Question Understanding for Electronic Health RecordsR00LM012104 · NLM · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ROBERTS, KIRK EDWARD · 2016 to 2018
$747k
NCATS NIH HHS U01 TR002062NCI NIH HHS U24 CA194215NLM NIH HHS R00 LM012104NLM NIH HHS R01 LM010681
6 · The paper itself

Abstract

Natural language processing (NLP) is useful for extracting information from clinical narratives, and both traditional machine learning methods and more-recent deep learning methods have been successful in various clinical NLP tasks. These methods often depend on traditional word embeddings that are outputs of language models (LMs). Recently, methods that are directly based on pre-trained language models themselves, followed by fine-tuning on the LMs (e.g. the Bidirectional Encoder Representations from Transformers (BERT)), have achieved state-of-the-art performance on many NLP tasks. Despite their success in the open domain and biomedical literature, these pre-trained LMs have not yet been applied to the clinical relation extraction (RE) task. In this study, we developed two different implementations of the BERT model for clinical RE tasks. Our results show that our tuned LMs outperformed previous state-of-the-art RE systems in two shared tasks, which demonstrates the potential of LM-based methods on the RE task.

Indexed as

Machine LearningNatural Language ProcessingDatasets as TopicHumansInformation Storage and RetrievalNarrationSemantics

Identifiers

PMID32308921
PMCPMC7153059
OpenAlexW3027260829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.