Evidence map›Paper›PMID 32308812›Full record

Observational studyAMIA ... Annual Symposium proceedings. AMIA Symposium2019

Evaluating the Portability of an NLP System for Processing Echocardiograms: A Retrospective, Multi-site Observational Study.

Prakash Adekkanattu, Guoqian Jiang, Yuan Luo, Paul R Kingsbury, Zhenxing Xu, Luke V Rasmussen, Jennifer A Pacheco, Richard C Kiefer, Daniel J Stone, Pascal S Brandt and 7 more

Open access · greenAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  8. Characterizing variability of electronic health record-driven phenotype definitions.Journal of the American Medical Informatics Association : JAMIA · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Prakash AdekkanattuWeill Cornell Medicine, New York, NY.
Guoqian JiangMayo Clinic, Rochester, MN.
Yuan LuoNorthwestern University, Chicago, IL.
Paul R KingsburyMayo Clinic, Rochester, MN.
Zhenxing XuWeill Cornell Medicine, New York, NY.
Luke V RasmussenNorthwestern University, Chicago, IL.
Jennifer A PachecoNorthwestern University, Chicago, IL.
Richard C KieferNorthwestern University, Chicago, IL.
Daniel J StoneMayo Clinic, Rochester, MN.
Pascal S BrandtUniversity of Washington, Seattle, WA.
Liang YaoNorthwestern University, Chicago, IL.
Yizhen ZhongNorthwestern University, Chicago, IL.
Yu DengNorthwestern University, Chicago, IL.
Fei WangWeill Cornell Medicine, New York, NY.
Jessica S AnckerWeill Cornell Medicine, New York, NY.
Thomas R CampionWeill Cornell Medicine, New York, NY.
Jyotishman PathakWeill Cornell Medicine, New York, NY.
Cornell University · USMayo Clinic in Arizona · USUniversity of Washington · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Genomic Basis of Susceptibility to COVID-19 Infection and its ComplicationsU01HG006379 · NHGRI · MAYO CLINIC ROCHESTER · PI Richard R. Sharp · 2011 to 2026
$16.5M
National Infrastructure for Standardized and Portable EHR Phenotyping AlgorithmsR01GM105688 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUO, YUAN, PATHAK, JYOTISHMAN · 2013 to 2020
$5.7M
Genomic Medicine at Northwestern: Discovery and ImplementationU01HG008673 · NHGRI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHISHOLM, REX L, SMITH, MAUREEN E · 2015 to 2019
$4.1M
Tools for standardizing clinical research metadata using HL7 FHIRU01HG009450 · NHGRI · MAYO CLINIC ROCHESTER · PI JIANG, GUOQIAN · 2016 to 2018
$1.4M
NCATS NIH HHS UL1 TR001422NHGRI NIH HHS U01 HG006379NHGRI NIH HHS U01 HG008673NHGRI NIH HHS U01 HG009450NIGMS NIH HHS R01 GM105688
6 · The paper itself

Abstract

While natural language processing (NLP) of unstructured clinical narratives holds the potential for patient care and clinical research, portability of NLP approaches across multiple sites remains a major challenge. This study investigated the portability of an NLP system developed initially at the Department of Veterans Affairs (VA) to extract 27 key cardiac concepts from free-text or semi-structured echocardiograms from three academic edical centers: Weill Cornell Medicine, Mayo Clinic and Northwestern Medicine. While the NLP system showed high precision and recall easurements for four target concepts (aortic valve regurgitation, left atrium size at end systole, mitral valve regurgitation, tricuspid valve regurgitation) across all sites, we found moderate or poor results for the remaining concepts and the NLP system performance varied between individual sites.

Indexed as

EchocardiographyElectronic Health RecordsHealth Information InteroperabilityNatural Language ProcessingHeartHeart Valve DiseasesHumansNarrationRetrospective Studies

Identifiers

PMID32308812
PMCPMC7153064
OpenAlexW2944017968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.