Evidence map›Paper›PMID 32308808›Full record

ArticleOxidative medicine and cellular longevity2020

Effects of Saccharides from Arctium lappa L. Root on FeCl

Tiantian Qiu, Hailun Zhou, Suying Li, Nuoya Tian, Zhe Li, Rui Wang, Pengyuan Sun, Jinyong Peng, Jianling Du, Xiaochi Ma and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Immunopharmacological potential ofFrontiers in pharmacology · 2025
    Review
  4. Saccharides fromExperimental and therapeutic medicine · 2022
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Tiantian QiuDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Hailun ZhouDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Suying LiDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Nuoya TianDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Zhe LiDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Rui WangDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Pengyuan SunDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Jinyong PengDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Jianling DuDepartment of Endocrinology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.ORCID https://orcid.org/0000-0001-9042-6969
Xiaochi MaDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Yunpeng DiaoDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.
Li LvDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.ORCID https://orcid.org/0000-0003-1157-853X
Li WangDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.ORCID https://orcid.org/0000-0003-2341-345X
Hua LiDepartment of Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning Province, China.ORCID https://orcid.org/0000-0002-7832-0229
Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saccharides from Arctium lappa. L. root (ALR-S) is a high-purity fructosaccharide separated from the medicinal plant Arctium lappa. L. root. These compounds showed many pharmacological effects in previous studies. In the present study, the antithrombotic effects of ALR-S in arterial thrombosis via inhibiting platelet adhesion and rebalancing thrombotic and antithrombotic factor expression and secretion were found in rats and human aortic endothelial cells (HAECs). This study also showed that inhibition of oxidative stress (OS), which is closely involved in the expression of coagulation- and thrombosis-related proteins, was involved in the antithrombotic effects of ALR-S. Furthermore, studies using FeCl

Indexed as

AnimalsArctiumHumansMaleMAP Kinase Signaling SystemNF-kappa BPlant RootsPlants, MedicinalRatsRats, Sprague-DawleySignal TransductionThrombosisNF-kappa B

Identifiers

PMID32308808
PMCPMC7132581
OpenAlexW3013993415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.