Evidence map›Paper›PMID 32308765›Full record

ArticleTheranostics2020

Extracellular vesicles from human umbilical cord blood plasma modulate interleukin-2 signaling of T cells to ameliorate experimental autoimmune encephalomyelitis.

Sueon Kim, Ji-Young Maeng, Seung-Joo Hyun, Hyun-Jung Sohn, Su-Yeon Kim, Cheol-Hwa Hong, Tai-Gyu Kim

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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  8. Therapeutic Application of Exosomes in Inflammatory Diseases.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sueon KimDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ji-Young MaengDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Seung-Joo HyunDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Hyun-Jung SohnCatholic Hematopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Su-Yeon KimCatholic Hematopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Cheol-Hwa HongDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Tai-Gyu KimDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Catholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human umbilical cord blood (UCB) cell-derived extracellular vesicles (EV) reportedly play immunosuppressive roles; however, UCB plasma-derived extracellular vesicles (CBP EVs) remain poorly studied. We examined the immunosuppressive potential of CBP EVs compared to that of adult blood plasma-derived extracellular vesicles (ABP EVs)

Indexed as

AnimalsCell DifferentiationCell LineCytokinesDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalExtracellular VesiclesHumansImmunosuppression TherapyInterleukin-2Leukocytes, MononuclearLymphocyte ActivationMatrix Metalloproteinase 9Mesenchymal Stem CellsMiceMice, Inbred C57BLCytokinesInterleukin-2Matrix Metalloproteinase 9MMP9 protein, humanexperimental autoimmune encephalomyelitis (EAE)interleukin-2 (IL-2) signalingmatrix metalloproteinase-9 (MMP-9)regulatory T cell (Treg)umbilical cord blood plasma-derived extracellular vesicles (CBP EVs)

Identifiers

PMID32308765
PMCPMC7163430
OpenAlexW3015920533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.