ArticleGastroenterology research and practice2020
Gastrointestinal Bleeding due to Pancreatic Disease-Related Portal Hypertension.
Article in Gastroenterology research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Anticoagulation Therapy for Splanchnic Vein Thrombosis Associated With Acute Pancreatitis: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisPooled it
- Treatment Strategy for Gastric Variceal Bleeding Caused by Sinistral Portal Hypertension Based on Hemodynamic Characteristics: A Case Report.Iranian journal of medical sciences · 2026Article
- nnU-Net-based CT segmentation of perigastric varices in sinistral portal hypertension: a multicenter study.Abdominal radiology (New York) · 2026Article
- Life-threatening upper gastrointestinal bleeding caused by pancreatic pseudocysts: A case report.Medicine · 2026Article
- Article
- Case report: Upper gastrointestinal bleeding associated with pancreatic segmental portal hypertension: six case reports and literature review.Frontiers in medicine · 2025Article
- Development of a nomogram for predicting pancreatic portal hypertension in patients with acute pancreatitis: a retrospective study.BMJ open gastroenterology · 2024Article
- Patterns of venous collateral development after splenic vein occlusion associated with surgical and oncological outcomes after distal pancreatectomy.Annals of gastroenterological surgery · 2024Article
- Safety and efficacy of modified endoscopic ultrasound-guided selective N-butyl-2-cyanoacrylate injections for gastric variceal hemorrhage in left-sided portal hypertension.World journal of gastrointestinal endoscopy · 2024Article
- SplenectomyTherapeutic advances in gastroenterology · 2024Article
- Splenic Hilar Involvement and Sinistral Portal Hypertension in Unresectable Pancreatic Tail Cancer.Cancers · 2023Article
- Two Cases of Gastric Varices with Left-sided Portal Hypertension Due to Essential Thrombocythemia Treated with Gastric Devascularization or Partial Splenic Embolization.Internal medicine (Tokyo, Japan) · 2023Article
- Splenic artery embolization for the treatment of pancreatic portal hypertension complicated by gastric variceal haemorrhage.Przeglad gastroenterologiczny · 2023Article
- Modified endoscopic ultrasound-guided selective N-butyl-2-cyanoacrylate injections for gastric variceal hemorrhage in left-sided portal hypertension: A case report.World journal of clinical cases · 2022Article
- The clinical applicability of percutaneous splenic vein stent implantation for pancreatic portal hypertension.BMC gastroenterology · 2022Article
- Preoperative splenic artery embolism followed by splenectomy is safe and effective in patients with sinistral portal hypertension.Langenbeck's archives of surgery · 2022Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsLeft-sided portal hypertension (LSPH) is a rare type of portal hypertension, which occurs due to obstruction, stenosis, or thrombosis within the splenic vein. Pancreatic diseases are the most common etiology of LSPH. This study is aimed at reporting our experiences and discussing the presentation, management, and prognosis of LSPH secondary to pancreatic diseases.
resultsThree elderly patients (>60 years old) were diagnosed with pancreatic cancer, of whom one underwent laparoscopic radical distal pancreatectomy and splenectomy, one received chemotherapy, and another one chose conservative management due to multiple systemic metastases. Two younger patients (<40 years old) were diagnosed with acute recurrent pancreatitis and chronic pancreatitis. Four of these five included patients presented with hematemesis and/or melena at our admission. All patients had gastric varices, and one of them also had esophageal varices. One elderly patient with metastatic pancreatic cancer underwent endoscopic variceal treatment as a rescue therapy but finally died of refractory gastrointestinal (GI) bleeding; another younger patient with chronic pancreatitis died of massive GI bleeding; and the remaining three patients survived at their last follow-up.
conclusionsLSPH should be seriously taken into consideration in patients with pancreatic diseases who develop upper GI bleeding. Clinicians should individualize the treatment strategy of LSPH according to the patients' clinical conditions and nature of pancreatic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.