Evidence map›Paper›PMID 32308603›Full record

ArticleCase reports in oncology

Is Gonadal Therapy a Promoter of Breast Cancer? Incidence of Breast Cancer in a Cohort of Survivors of Oncological Diseases Treated with Gonadal Steroids.

Daniela Dias, Susana Esteves, Sónia Andrade, Joana Maciel, Daniela Cavaco, Joana Simões-Pereira, Maria Conceição Pereira

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Daniela DiasEndocrinology Department, Portuguese Cancer Institute of Lisbon, Lisbon, Portugal.
Susana EstevesClinical Research Department, Portuguese Cancer Institute of Lisbon, Lisbon, Portugal.
Sónia AndradeEndocrinology Department, Portuguese Cancer Institute of Lisbon, Lisbon, Portugal.
Joana MacielEndocrinology Department, Portuguese Cancer Institute of Lisbon, Lisbon, Portugal.
Daniela CavacoEndocrinology Department, Portuguese Cancer Institute of Lisbon, Lisbon, Portugal.
Joana Simões-PereiraEndocrinology Department, Portuguese Cancer Institute of Lisbon, Lisbon, Portugal.
Maria Conceição PereiraEndocrinology Department, Portuguese Cancer Institute of Lisbon, Lisbon, Portugal.
Instituto Português de Oncologia Francisco Gentil · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a great controversy about hormonal replacement therapy in women among the members of the scientific community. Cancer survivors have sometimes had their ovary function totally or partially destroyed, thus affecting their development and quality of life. In this study, we were looking for adverse effects caused, eventually, by estroprogestative therapy in a cohort of supplemented survivors. The occurrence of breast cancer was our main concern. Ours is a retrospective study based on the clinical records of 174 survivors of several cancer diseases. Their median ages within each of the following time frames were: diagnosis - 22 years old; start of endocrine treatment - 26 years old, and duration of treatment - 12 years old. Evaluation was composed of breast cancer assessment, osteopenia and osteoporosis incidence, and vascular events. We have found a very low incidence of breast cancer as well as of vascular events. After treatment, a high percentage of our sample displayed bone mass improvement.

Indexed as

Breast cancerHormonal replacement therapyOncological survivors

Identifiers

PMID32308603
PMCPMC7154255
OpenAlexW3014846771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.