Evidence map›Paper›PMID 32308555›Full record

ArticleMediators of inflammation2020

Complement Activation in Association with Markers of Neutrophil Extracellular Traps and Acute Myocardial Infarction in Stable Coronary Artery Disease.

Karsten E Kluge, Miriam S Langseth, Trine B Opstad, Alf Å Pettersen, Harald Arnesen, Theis Tønnessen, Ingebjørg Seljeflot, Ragnhild Helseth

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Neutrophil extracellular traps: a catalyst for atherosclerosis.Molecular and cellular biochemistry · 2024
    Review
  6. Neutrophil extracellular traps in homeostasis and disease.Signal transduction and targeted therapy · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Receptor-Mediated NETosis on Neutrophils.Frontiers in immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Karsten E KlugeCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Norway.ORCID https://orcid.org/0000-0002-6561-9037
Miriam S LangsethCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Norway.
Trine B OpstadCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Norway.ORCID https://orcid.org/0000-0002-9229-3132
Alf Å PettersenCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Norway.
Harald ArnesenCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Norway.
Theis TønnessenUniversity of Oslo, Norway.ORCID https://orcid.org/0000-0001-9853-100X
Ingebjørg SeljeflotCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Norway.ORCID https://orcid.org/0000-0003-4071-3358
Ragnhild HelsethCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Norway.ORCID https://orcid.org/0000-0001-5012-9214
Oslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complement activation and neutrophil extracellular traps (NETs) have both been suggested to drive atherosclerotic plaque progression. Although experimental studies suggest interplay between these two innate immunity components, the relevance in patients with coronary artery disease (CAD) is unclear. The aim of this study was to assess associations between complement activation and NETs in patients with stable CAD and examine the role of complement activation on clinical outcome. Blood samples from a cohort of patients with angiographically verified stable CAD (

Indexed as

AdultAgedAged, 80 and overBiomarkersComplement ActivationCoronary Artery DiseaseExtracellular TrapsFemaleHumansMaleMiddle AgedMyocardial InfarctionPeroxidaseBiomarkersPeroxidase

Identifiers

PMID32308555
PMCPMC7136779
OpenAlexW3013773691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.