Evidence map›Paper›PMID 32308548›Full record

ArticleInternational journal of medical sciences2020

Piwi-interacting RNAs play a role in vitamin C-mediated effects on endothelial aging.

Sulin Zheng, Haoxiao Zheng, Anqing Huang, Linlin Mai, Xiaohui Huang, Yunzhao Hu, Yuli Huang

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Biomarkers of Oxidative Stress Tethered to Cardiovascular Diseases.Oxidative medicine and cellular longevity · 2022
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sulin ZhengDepartment of cardiology, Shunde hospital, Southern Medical University (The first people's hospital of Shunde, Foshan), Guangdong, China.
Haoxiao ZhengDepartment of cardiology, Shunde hospital, Southern Medical University (The first people's hospital of Shunde, Foshan), Guangdong, China.
Anqing HuangDepartment of cardiology, Shunde hospital, Southern Medical University (The first people's hospital of Shunde, Foshan), Guangdong, China.
Linlin MaiDepartment of cardiology, Shunde hospital, Southern Medical University (The first people's hospital of Shunde, Foshan), Guangdong, China.
Xiaohui HuangDepartment of cardiology, Shunde hospital, Southern Medical University (The first people's hospital of Shunde, Foshan), Guangdong, China.
Yunzhao HuDepartment of cardiology, Shunde hospital, Southern Medical University (The first people's hospital of Shunde, Foshan), Guangdong, China.
Yuli HuangDepartment of cardiology, Shunde hospital, Southern Medical University (The first people's hospital of Shunde, Foshan), Guangdong, China.
The First People's Hospital of Shunde · CNSecond Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The underlying mechanisms that mediate the effects of vitamin C on endothelial cell aging are widely unknown. To investigate whether Piwi-interacting RNAs (piRNAs) are involved in this process, an endothelial aging model was induced

Indexed as

Ascorbic AcidCellular SenescenceGene Expression RegulationHumansHuman Umbilical Vein Endothelial CellsHydrogen PeroxideRNA, Small InterferingAscorbic AcidHydrogen PeroxideRNA, Small Interferingagingendothelial cellsPiwi-interacting RNAsvitamin C

Identifiers

PMID32308548
PMCPMC7163353
OpenAlexW3016009739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.