ReviewClinical and experimental gastroenterology2020
Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current Management.
Review in Clinical and experimental gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Cholangiohydatidosis. Clinical features, postoperative complications and hospital mortality. A systematic review.PLoS neglected tropical diseases · 2024Pooled it
- Evaluation of the necessity of simultaneous cholecystectomy in patients undergoing liver hydatid cyst surgery.Surgery open science · 2025Article
- Multiseptate gallbladder in a pediatric pateint: A case report and review of literature.International journal of surgery case reports · 2024Article
- Liver hydatid cyst rupture into gallbladder and right hepatic duct: A case report.International journal of surgery case reports · 2024Article
- Liver hydatidosis disease with portal vein invasion: Report of a rare case and review of literature.Radiology case reports · 2024Article
- Laparoscopic management of a primary gallbladder hydatid cyst with daughter cysts in the common bile duct: Case report.Annals of medicine and surgery (2012) · 2022Article
- Article
- Gallbladder Hydatid Disease Complicated with Multiple Hepatobiliopancreatic Fistulae: A Case Report.Iranian journal of parasitologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGallbladder hydatid cyst (GBHC) is highly uncommon with an incidence of 0.3-0.4% of all atypically located hydatid cysts. Our personal experience of one case of primary GBHC (PGBHC) managed laparoscopically motivated this systematic review. This study aimed to analyze the demographic characteristics, types [whether primary GBHC (PGBHC) or secondary GBHC (SGBHC)], clinical presentation, laboratory investigations, imaging studies, operative procedure, hospital stay, follow-up and recurrence.
methodsA systematic review was performed using preferred reporting items for systematic reviews and meta-analyses guidelines.
resultsTwenty studies, including 22 cases plus one more case managed by us, were included in the review. For PGBHC, the mean age was 48.61 years while for SGBHC it was 47.9 years. PGBHC was more common in females (69.23%) while SGBHC was more common in males (55.55%). Overall, GBHC was more common in females (56.52%). The most common presentation overall was abdominal pain (100%) followed by nausea/vomiting (43.47%). The other common symptoms were nausea/vomiting (61.53%) and Murphy's sign (38.46%) in PGBHC, but jaundice (50%) and fever (30%) in SGBHC. In PGBHC, 50% patients had normal liver function while this was deranged in 66.66% patients with SGBHC. Serology was positive in 50% of PGBHC and 100% in SGBHC. Ultrasonography was positive in 50%, while CT-scan showed 70%. CT-scan was better at detection of SGBHC (100%). The most common operation was open cholecystectomy (78.26%) either isolated or combined. Isolated open cholecystectomy was commonly done in PGBHC (69.23%). Overall, only 56.52% of patients received albendazole, but no recurrence was reported. The average hospital stay was 7.25 days and follow-up ranged from 1 month to 10 years.
conclusionGBHC mostly affects females with abdominal pain being the most common symptom. Ultrasonography is expedient though CT-scan is more sensitive. Albendazole monotherapy has questionable value. Open cholecystectomy is the most common operation. However, laparoscopy is safe in experienced hands.
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