Evidence map›Paper›PMID 32308460›Full record

ArticleClinical, cosmetic and investigational dermatology2020

Expert Consensus on Injection Technique and Area-Specific Recommendations for the Hyaluronic Acid Dermal Filler VYC-12L to Treat Fine Cutaneous Lines.

Patricia Ogilvie, Jesper Thulesen, Christophe Leys, Dimitris Sykianakis, Jonquille Chantrey, Marva Safa, Vitor Figueiredo, Izolda Heydenrych, Maurizio Cavallini, Elin Kringen Langeland and 1 more

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Treating Aging Changes of Facial Anatomical Layers with Hyaluronic Acid Fillers.Clinical, cosmetic and investigational dermatology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Patricia OgilvieSkinConcept, Munich, Germany.ORCID 0000-0002-4908-6787
Jesper ThulesenClinic Aesthetica, Copenhagen, Denmark.
Christophe LeysMedical Skincare, Sint-Truiden, Belgium.
Dimitris SykianakisWell Aging Clinic, Athens, Greece.
Jonquille ChantreyExpert Aesthetics, Cheshire, UK.
Marva SafaLa Jouvence, Neuchâtel, Switzerland.ORCID 0000-0003-4154-359X
Vitor FigueiredoUp Clinic Lisboa, Lisbon, Portugal.ORCID 0000-0001-9163-4153
Izolda HeydenrychCosmetic Dermatology Centre, Cape Town, South Africa.ORCID 0000-0002-5660-8520
Maurizio CavalliniServizio di Chirurgia Plastica, Centro Diagnostico Italiano, Milan, Italy.
Elin Kringen LangelandInjeksjonsspesialisten AS, Trondheim, Norway.
Anne WetterDiagnostiskt Centrum Hud, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVYC-12L is a hyaluronic acid (HA) injectable gel designed to treat fine cutaneous lines and improve skin quality attributes such as hydration and elasticity.

objectiveExpert consensus was sought on VYC-12L injection technique and primary treatment target areas.

methodsA multinational group of aesthetic medicine clinicians (n = 128) attended product training and each identified ~10 patients for VYC-12L. After treating their first and last patients, the clinicians completed a survey on preferred injection methodology/technique, including injection angle, volume, and spacing. An expert panel (n = 12) discussed survey results and their clinical experiences to obtain consensus on VYC-12L technique and appropriate treatment areas.

resultsRecommendations included micro-depot injections of VYC-12L into the deep dermis with a 32G ½ inch needle inserted at <45º to the skin, spaced 0.5‒1.0 cm apart, with 0.01‒0.05 mL volume per injection (full-face total volume: ~2 mL). Recommended primary treatment areas were the malar, perioral, neck, and décolletage regions. Injection techniques for different treatment areas/demographic characteristics were similar, with some variability in treatment approach. Patient selection criteria, pre- and post-treatment guidelines, and managing patient expectations are important components of treatment.

conclusionThese consensus recommendations may assist clinicians in optimizing the treatment of fine lines with VYC-12L.

Indexed as

consensusdermishyaluronic acidinjectable dermal fillerJuvéderm Voliteskin aging

Identifiers

PMID32308460
PMCPMC7152505

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.