Evidence map›Paper›PMID 32308051›Full record

ArticleDrug delivery2020

Xueyan Liu, Liangke Zhang, Wengao Jiang, Zhangyou Yang, Zongjie Gan, Chao Yu, Ran Tao, Huali Chen

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Red blood cells: a potential delivery system.Journal of nanobiotechnology · 2023
    Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xueyan LiuCollege of Pharmacy, Chongqing Medical University, Chongqing, China.
Liangke ZhangCollege of Pharmacy, Chongqing Medical University, Chongqing, China.
Wengao JiangCollege of Pharmacy, Chongqing Medical University, Chongqing, China.
Zhangyou YangCollege of Pharmacy, Chongqing Medical University, Chongqing, China.
Zongjie GanCollege of Pharmacy, Chongqing Medical University, Chongqing, China.
Chao YuCollege of Pharmacy, Chongqing Medical University, Chongqing, China.
Ran TaoCollege of Pharmacy, Chongqing Medical University, Chongqing, China.
Huali ChenCollege of Pharmacy, Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNChongqing Medical and Pharmaceutical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic cardiac disease (ICD) is a cardiovascular disease with high morbidity and mortality. In this study, a novel myocardial targeted drug delivery system was developed represented by co-modified liposomes consisting of red cell membrane (RCM), and the peptides TAT and PCM. Liposomes were prepared using a membrane dispersion-ultrasonic method; the prepared 1% TAT and 3% PCM micelles were mixed with liposomes and under overnight stirring to form polypeptid-modified liposomes. RCM was isolated from mice blood, and the mechanical force facilitated RCM adhesion to the lipid bilayer. The characteristics of liposomes such as the morphology, particle size, zeta-potential, and RCM-conjugation to lipsomes were evaluated. Uptake efficiency and cellular toxicity of liposomes were evaluated

Indexed as

AnimalsCell LineDrug CarriersErythrocyte MembraneLiposomesMaleMiceMyocardiumParticle SizePeptidesTissue DistributionDrug CarriersLiposomesPeptidesliposomesMyocardium deliveryPCMred cell membraneTAT

Identifiers

PMID32308051
PMCPMC7191910
OpenAlexW3016616850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.