Evidence map›Paper›PMID 32308018›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Epoxyeicosatrienoic acid metabolites inhibit Kir4.1/Kir5.1 in the distal convoluted tubule.

Ming-Xiao Wang, Li-Jun Wang, Yu Xiao, Dan-Dan Zhang, Xin-Peng Duan, Wen-Hui Wang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Ming-Xiao WangDepartment of Physiology, Zhuhai Campus of Zunyi Medical University, Zunyi, Guizhou, China.
Li-Jun WangDepartment of Physiology, Harbin Medical University, Harbin, China.
Yu XiaoDepartment of Physiology, Qiqihar Medical College, Heilongjiang, China.
Dan-Dan ZhangDepartment of Pharmacology, New York Medical College, Valhalla, New York.
Xin-Peng DuanDepartment of Pharmacology, New York Medical College, Valhalla, New York.
Wen-Hui WangDepartment of Pharmacology, New York Medical College, Valhalla, New York.
New York Medical College · USHarbin Medical University · CNQiqihar Medical University · CNZunyi Medical University · CN

Funding

Role of Kir4.1 in Regulating NCC and ROMK in DCTR01DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2001 to 2020
$7.4M
Role of Kir4.1 in Regulating NCC and ROMK in DCTR56DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2021 to 2021
$100k
NIDDK NIH HHS R01 DK054983NIDDK NIH HHS R56 DK054983
6 · The paper itself

Abstract

Cytochrome

Indexed as

8,11,14-Eicosatrienoic AcidAmidesAnimalsArachidonic AcidCytochrome P450 Family 2Enzyme InhibitorsKcnj10 ChannelKidney Tubules, DistalKir5.1 ChannelMaleMembrane PotentialsMice, 129 StrainMice, KnockoutPotassium Channel BlockersPotassium Channels, Inwardly Rectifying11,12-epoxy-5,8,14-eicosatrienoic acid14,15-epoxy-5,8,11-eicosatrienoic acid8,11,14-Eicosatrienoic AcidAmidesArachidonic AcidCyp2c23 protein, mouseCytochrome P450 Family 2Enzyme InhibitorsKcnj10 ChannelKcnj16 protein, mouseKir5.1 ChannelN-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamidePotassium Channel BlockersPotassium Channels, Inwardly Rectifyingaldosterone-sensitive distal nephroncytochrome P-450 epoxygenaseeicosanoidshypertensionNa+-Cl− cotransporterthiazide sensitive

Identifiers

PMID32308018
PMCPMC7311705
OpenAlexW3016793354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.