Evidence map›Paper›PMID 32308017›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Integrin-β

Miran Yoo, Laura M C Barisoni, Kyung Lee, G Luca Gusella

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Ciliary-Mediated Mechanotransduction in Skeletal Development and Diseases.Results and problems in cell differentiation · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Computational study of biomechanical drivers of renal cystogenesis.Biomechanics and modeling in mechanobiology · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miran YooDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Laura M C BarisoniDepartments of Pathology and Medicine, Duke University, Durham, North Carolina.
Kyung LeeDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0002-9756-1765
G Luca GusellaDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

Funding

The Role of LRG1 in Diabetic Kidney DiseaseR01DK117913 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Bhaskar Chandra Das, Kyung Lee · 2018 to 2026
$2.6M
Mechanisms of ADPKD cystogenesisR01DK106035 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GUSELLA, GABRIELE LUCA · 2016 to 2020
$1.9M
NIDDK NIH HHS R01 DK106035NIDDK NIH HHS R01 DK117913
6 · The paper itself

Abstract

Defects in the function of primary cilia are commonly associated with the development of renal cysts. On the other hand, the intact cilium appears to contribute a cystogenic signal whose effectors remain unclear. As integrin-β

Indexed as

AnimalsAquaporin 2CiliaCytokinesDisease Models, AnimalFibrosisInflammation MediatorsIntegrin beta1KidneyKidney Diseases, CysticMacrophagesMice, KnockoutSignal TransductionTumor Suppressor ProteinsAqp2 protein, mouseAquaporin 2CytokinesInflammation MediatorsIntegrin beta1Itgb1 protein, mouseTg737Rpw protein, mouseTumor Suppressor Proteinsciliopathyciliumcystic kidneyIft88integrin

Identifiers

PMID32308017
PMCPMC7294335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.