ArticleBritish journal of clinical pharmacology2020
Extensive hard palate hyperpigmentation associated with chloroquine use.
Article in British journal of clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- ENT symptoms in acute COVID-19: a narrative review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2022Review
- Oral pigmentation as an adverse effect of chloroquine and hydroxychloroquine use: A scoping review.Medicine · 2022Article
- COVID-19 and Its Repercussions on Oral Health: A Review.Medicina (Kaunas, Lithuania) · 2021Review
- Oral mucosal lesions in a COVID-19 patient: New signs or secondary manifestations?International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
- Future Challenges of Covid-19 and Oral Manifestations in Daily Dental Practice: A Literature Review.Journal of International Society of Preventive & Community DentistryReview
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 66-year-old woman diagnosed clinical manifestation of extensive hard palate hyperpigmentation is presented. Due to historic of rheumatoid arthritis and use of chloroquine phosphate for 3 years, exogenous hyperpigmentation associated with the drug was included among the possible diagnoses. Incisional biopsy was performed and the histopathological exam confirmed exogenous hyperpigmentation compatible with chloroquine use. The patient was referred to the rheumatologist and the ophthalmologist for evaluation of the continuity of the chloroquine use. After one year of follow-up, no changes were seen in the hyperpigmentation nor other clinical changes. Hyperpigmentation of the hard palate by the use of chloroquine is one of the adverse effects of the chronic use of this drug and does not require specific treatment. The adequate anamnesis and the knowledge about the adverse effects of the drug allowed an adequate therapeutic approach in the case.
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