Evidence map›Paper›PMID 32306982›Full record

ArticleTrials2020

Supporting caregivers of veterans with Alzheimer's disease and traumatic brain injury: study protocol for a randomized controlled trial.

Jennifer L Carnahan, Katherine S Judge, Joanne K Daggy, James E Slaven, Nicki Coleman, Emily L Fortier, Christopher Suelzer, Nicole R Fowler

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03397667 (The Aging Brain ANSWERS Program), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03397667 nacompletednot on this map

The Aging Brain ANSWERS Program: Veterans Living With Alzheimer's and Traumatic Brain Injury and Caregiver Burden

TypeinterventionalSponsorIndiana UniversityRan2018 to 2023Enrolled236ConditionsTraumatic Brain Injury, Alzheimer Disease, Veterans, Family CaregiversArmsABC ANSWERS, Control
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jennifer L CarnahanDepartment of Medicine, Indiana University School of Medicine, 1101 West 10th Street, Indianapolis, IN, 46202, USA.
Katherine S JudgeDepartment of Psychology, College of Sciences and Health Professions, Cleveland State University, 1836 Euclid Avenue, Cleveland, OH, USA.
Joanne K DaggyDepartment of Biostatistics, Indiana University School of Medicine, 410 West 10th Street, Suite 3000, Indianapolis, IN, 46202, USA.
James E SlavenDepartment of Biostatistics, Indiana University School of Medicine, 410 West 10th Street, Suite 3000, Indianapolis, IN, 46202, USA.
Nicki ColemanRegenstrief Institute, Indiana University Center for Aging Research, Indianapolis, USA.
Emily L FortierRegenstrief Institute, Indiana University Center for Aging Research, Indianapolis, USA.
Christopher SuelzerRichard L. Roudebush VA Medical Center Research Services, 1481 West 10th Street, Indianapolis, IN, 46202, USA.
Nicole R FowlerDepartment of Medicine, Indiana University School of Medicine, 1101 West 10th Street, Indianapolis, IN, 46202, USA. fowlern@iupui.edu.
Indiana University – Purdue University Indianapolis · USIndiana University School of MedicineCleveland State University · US

Funding

U.S. Department of Defense W81XWH-17-1-0574
6 · The paper itself

Abstract

backgroundPatients with Alzheimer's disease and related dementias (ADRD) and traumatic brain injury (TBI) and their caregivers require cognitive and behavioral symptom management, interdisciplinary care, support for caregivers, and seamless care coordination between providers. Caring for someone with ADRD or TBI is associated with higher rates of psychological morbidity and burden, social isolation, financial hardship, and deterioration of physical health. Tremendous need exists for primary care-based interventions that concurrently address the care needs of dyads and aim to improve care and outcomes for both individuals with ADRD and TBI and their family caregivers.

methodsThe Aging Brain Care Acquiring New Skills While Enhancing Remaining Strengths (ABC ANSWERS) study is a randomized controlled trial that tests the effectiveness of an intervention based on two evidence-based programs that have been developed for and previously tested in populations with ADRD, TBI, stroke, and late-life depression and/or who have survived an intensive care unit stay. This study includes 200 dyads comprised of a veteran with a diagnosis of ADRD or TBI and the veteran's primary informal caregiver. Dyads are randomized to receive the ABC ANSWERS intervention or routine Veterans Health Administration (VHA) primary care with a standardized educational and resource information packet. Data collection occurs at baseline and three follow-up time points (3 months, 6 months, and 12 months). The primary outcome is caregiver quality of life (QoL). A secondary measure for the caregiver is caregiver burden. Secondary measures for both the veteran and caregiver include symptoms of depression and anxiety. DISCUSSION: The ABC ANSWERS intervention integrates common features of an evidence-based collaborative care model for brain health while concurrently attending to the implementation barriers of delivering care and skills to dyads. We hypothesize that caregivers in dyads randomized to the ABC ANSWERS program will experience higher levels of QoL and lower levels of depression, anxiety, dyadic strain, and caregiver burden at 12 months than those receiving usual VHA primary care.

trial registrationClinicalTrials.gov, NCT03397667. Registered on 12 January 2018.

Indexed as

Adaptation, PsychologicalAdolescentAdultAgedAged, 80 and overAlzheimer DiseaseAnxietyBrain Injuries, TraumaticCaregiversDepressionEarly Medical InterventionFemaleFollow-Up StudiesHealth Care CostsHumansMaleAlzheimer’s diseaseCaregiversCollaborative careDementiaQuality of lifeTraumatic brain injuryVeterans

Identifiers

PMID32306982
PMCPMC7168967
OpenAlexW3016441615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.