Evidence map›Paper›PMID 32306853›Full record

ArticleEmerging microbes & infections2020

Development of a reverse transcription-loop-mediated isothermal amplification as a rapid early-detection method for novel SARS-CoV-2.

Yun Hee Baek, Jihye Um, Khristine Joy C Antigua, Ji-Hyun Park, Yeonjae Kim, Sol Oh, Young-Il Kim, Won-Suk Choi, Seong Gyu Kim, Ju Hwan Jeong and 7 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 181 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
181citing papers in PubMed, 8 pooled it
26.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

181 citing papers in PubMed, 8 syntheses or guidelines pooled it, 339 citations in OpenAlex.

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  14. Development and validation of a multi-platform LAMP system for rapid HAdV-3 and HAdV-7 detection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
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  17. Development of a Novel Nested-RT-LAMP Assay for the Rapid and Accurate Coronavirus Disease-2019 Diagnosis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
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121 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 3 countries.

Yun Hee BaekDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.ORCID https://orcid.org/0000-0002-8453-4880
Jihye UmResearch Institute of Public Health, National Medical Center, Seoul, Republic of Korea.
Khristine Joy C AntiguaDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.ORCID https://orcid.org/0000-0003-0711-1873
Ji-Hyun ParkDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.
Yeonjae KimCenter for Infectious Diseases Research, Department of Internal Medicine, National Medical Center, Seoul, Republic of Korea.
Sol OhDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.
Young-Il KimDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.
Won-Suk ChoiDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.ORCID https://orcid.org/0000-0002-5120-0374
Seong Gyu KimDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.
Ju Hwan JeongDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.ORCID https://orcid.org/0000-0001-7226-1507
Bum Sik ChinCenter for Infectious Diseases Research, Department of Internal Medicine, National Medical Center, Seoul, Republic of Korea.
Halcyon Dawn G NicolasDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.ORCID https://orcid.org/0000-0001-9409-2900
Ji-Young AhnSchool of Biological Sciences, Chungbuk National University, Cheongju, Republic of Korea.
Kyeong Seob ShinDepartment of Laboratory Medicine, Chungbuk National University College of Medicine, Cheongju, Republic of Korea.
Young Ki ChoiDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.
Jun-Sun ParkResearch Institute of Public Health, National Medical Center, Seoul, Republic of Korea.
Min-Suk SongDepartment of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Republic of Korea.ORCID https://orcid.org/0000-0001-6073-0783
Chungbuk National University · KRPublic Health Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The previous outbreaks of SARS-CoV and MERS-CoV have led researchers to study the role of diagnostics in impediment of further spread and transmission. With the recent emergence of the novel SARS-CoV-2, the availability of rapid, sensitive, and reliable diagnostic methods is essential for disease control. Hence, we have developed a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for the specific detection of SARS-CoV-2. The primer sets for RT-LAMP assay were designed to target the nucleocapsid gene of the viral RNA, and displayed a detection limit of 10

Indexed as

BetacoronavirusCoronavirus InfectionsCoronavirus Nucleocapsid ProteinsCOVID-19HumansLimit of DetectionNucleic Acid Amplification TechniquesNucleocapsid ProteinsPandemicsPhosphoproteinsPneumonia, ViralSARS-CoV-2Time FactorsCoronavirus Nucleocapsid Proteinsnucleocapsid phosphoprotein, SARS-CoV-2Nucleocapsid ProteinsPhosphoproteinscolorimetric detectionCOVID-19molecular diagnosisnovel coronavirusreverse transcription-loop-mediated isothermal amplificationSARS-CoV-2

Identifiers

PMID32306853
PMCPMC7301696
OpenAlexW3017152347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.