Evidence map›Paper›PMID 32306551›Full record

ArticleJournal of applied clinical medical physics2020

Technical Note: A novel dosimeter improves total skin electron therapy surface dosimetry workflow.

Irwin I Tendler, Petr Bruza, Michael Jermyn, Jennifer Soter, Gregory Sharp, Benjamin Williams, Lesley A Jarvis, Brian Pogue, David J Gladstone

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Irwin I TendlerThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Petr BruzaThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Michael JermynThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Jennifer SoterThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Gregory SharpDepartment of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA.
Benjamin WilliamsDepartment of Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.
Lesley A JarvisDepartment of Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.
Brian PogueThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
David J GladstoneThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Dartmouth College · USCotton (United States) · USDoseOptics (United States) · USDartmouth–Hitchcock Medical Center · USMassachusetts General Hospital · US

Funding

OPTICAL CHERENKOV IMAGING DOSIMETRY IN HUMAN RADIOTHERAPYR01EB023909 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI GLADSTONE, DAVID J., JARVIS, LESLEY A · 2017 to 2024
$4.4M
Optical imaging for radiation therapy dose verification on patientsR44CA199836 · NCI · DOSEOPTICS, LLC · PI WARE, WILLIAM · 2015 to 2016
$1.3M
NCI NIH HHS R44 CA199836NIBIB NIH HHS R01 EB023909NIH HHS CA023106NIH HHS CA199836NIH HHS EB023909NIH HHS P30NIH HHS R01NIH HHS R44
6 · The paper itself

Abstract

purposeThe novel scintillator-based system described in this study is capable of accurately and remotely measuring surface dose during Total Skin Electron Therapy (TSET); this dosimeter does not require post-exposure processing or annealing and has been shown to be re-usable, resistant to radiation damage, have minimal impact on surface dose, and reduce chances of operator error compared to existing technologies e.g. optically stimulated luminescence detector (OSLD). The purpose of this study was to quantitatively analyze the workflow required to measure surface dose using this new scintillator dosimeter and compare it to that of standard OSLDs.

methodsDisc-shaped scintillators were attached to a flat-faced phantom and a patient undergoing TSET. Light emission from these plastic discs was captured using a time-gated, intensified, camera during irradiation and converted to dose using an external calibration factor. Time required to complete each step (daily QA, dosimeter preparation, attachment, removal, registration, and readout) of the scintillator and OSLD surface dosimetry workflows was tracked.

resultsIn phantoms, scintillators and OSLDs surface doses agreed within 3% for all data points. During patient imaging it was found that surface dose measured by OSLD and scintillator agreed within 5% and 3% for 35/35 and 32/35 dosimetry sites, respectively. The end-to-end time required to measure surface dose during phantom experiments for a single dosimeter was 78 and 202 sec for scintillator and OSL dosimeters, respectively. During patient treatment, surface dose was assessed at 7 different body locations by scintillator and OSL dosimeters in 386 and 754 sec, respectively.

conclusionScintillators have been shown to report dose nearly twice as fast as OSLDs with substantially less manual work and reduced chances of human error. Scintillator dose measurements are automatically saved to an electronic patient file and images contain a permanent record of the dose delivered during treatment.

Indexed as

ElectronsRadiation DosimetersHumansPhantoms, ImagingRadiometryWorkflowdosimeterefficiencyoptical imagingOSLDscintillatorsurface dosimetryworkflow

Identifiers

PMID32306551
PMCPMC7324701
OpenAlexW3016441112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.