Evidence map›Paper›PMID 32306488›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2020

Hyperammonemia syndrome due to Ureaplasma infection after liver-kidney transplant.

Chase A Cannon, Maria A Corcorran, Kathryn W Shaw, Martin Montenovo, Lena Sibulesky, Jorge D Reyes, Stephen C Rayhill, Anne M Larson, Patricia A Kritek, Shewit Giovanni and 3 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Hyperammonemia After Lung Transplantation: Systematic Review and a Mini Case Series.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Pooled it
  2. Article
  3. Article
  4. Renal failure · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Frontiers in medicine · 2022
    Article
  10. A novel cause of emergent hyperammonemia:Molecular genetics and metabolism reports · 2021
    Article
  11. Impact of Screening and Treatment of Ureaplasma species on Hyperammonemia Syndrome in Lung Transplant Recipients: A Single Center Experience.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Chase A CannonDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-2962-754X
Maria A CorcorranDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Kathryn W ShawDivision of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.
Martin MontenovoDivision of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-8645-7797
Lena SibuleskyDivision of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-5435-737X
Jorge D ReyesDivision of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.
Stephen C RayhillDivision of Transplant Surgery, Department of Surgery, University of Washington, Seattle, Washington, USA.
Anne M LarsonDivision of Gastroenterology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Patricia A KritekDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.
Shewit GiovanniDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0003-2452-2201
Iris de CastroDivision of Nephrology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Nayan AroraDivision of Nephrology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Robert M RakitaDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0001-8105-8455
University of Washington · US

Funding

VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
RESPIRATORY RESEARCH TRAINING PROGRAMT32HL007287 · NHLBI · UNIVERSITY OF WASHINGTON · PI Kristina Anne Crothers, David J. Horne · 1985 to 2026
$16.7M
UNIVERSITY OF WASHINGTON GI TRAINING GRANTT32DK007742 · NIDDK · UNIVERSITY OF WASHINGTON · PI GRADY, WILLIAM MALLORY · 1996 to 2022
$4.7M
National Institute of Allergy and Infectious Diseases T32 AI007140-41NHLBI NIH HHS T32 HL007287NIAID NIH HHS T32 AI007140NIDDK NIH HHS T32 DK007742NIDDK NIH HHS T32 DK007742-22
6 · The paper itself

Abstract

Hyperammonemia syndrome, with high levels of ammonia and neurologic dysfunction, is a syndrome with historically high mortality that may occur after solid organ transplantation. Recently, this has been associated with infection due to Ureaplasma, mostly following lung transplantation. We describe the first case of hyperammonemia syndrome due to Ureaplasma infection after liver-kidney transplantation. Our patient rapidly recovered after specific antibiotic treatment. It is important to consider these infections in the differential diagnosis for encephalopathy post-transplant, as these organisms often do not grow using routine culture methods and polymerase chain reaction testing is typically required for their detection. This is particularly critical after liver transplantation, where a number of other etiologies may be considered as a cause of hyperammonemia syndrome.

Indexed as

Anti-Bacterial AgentsFemaleHumansHyperammonemiaKidney TransplantationLiver TransplantationMiddle AgedPostoperative ComplicationsTreatment OutcomeUreaplasmaUreaplasma InfectionsAnti-Bacterial Agentshyperammonemialiver transplantationUreaplasma

Identifiers

PMID32306488
PMCPMC7292677
OpenAlexW3016497868

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.