Evidence map›Paper›PMID 32306075›Full record

ArticleCancer immunology, immunotherapy : CII2020

Tumor-infiltrating CD39

Yu Qi, Yu Xia, Zhiyuan Lin, Yang Qu, Yangyang Qi, Yifan Chen, Quan Zhou, Han Zeng, Jiajun Wang, Yuan Chang and 11 more

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Tumor-specific but immunosuppressive CD39Cell reports. Medicine · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Yu QiDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yu XiaDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zhiyuan LinDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yang QuDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yangyang QiDepartment of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Yifan ChenDepartment of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Quan ZhouDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Han ZengDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Jiajun WangDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yuan ChangDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
Qi BaiDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yiwei WangDepartment of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yu ZhuDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
Le XuDepartment of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lingli ChenDepartment of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.
Yunyi KongDepartment of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.
Weijuan ZhangDepartment of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Bo DaiDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
Li LiuDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. liu.li@zs-hospital.sh.cn.
Jianming GuoDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. guo.jianming@zs-hospital.sh.cn.
Jiejie XuDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. jjxufdu@fudan.edu.cn.ORCID http://orcid.org/0000-0001-7431-9063
Sun Yat-sen University · CNFudan University · CNFudan University Shanghai Cancer Center · CNShanghai Jiao Tong University · CNShanghai Medical College of Fudan University · CN

Funding

Guide Project of Science and Technology Commission of Shanghai Municipality 17411963100National Key R&D Program of China 2017YFC0114303National Natural Science Foundation of China 31770851,81871306,81872082,81902556,81902563National Natural Science Foundation of China 81671628National Natural Science Foundation of China 81702496National Natural Science Foundation of China 81702497National Natural Science Foundation of China 81702805National Natural Science Foundation of China 81772696National Natural Science Foundation of China 81902898National Natural Science Foundation of China 81974393Shanghai Municipal Natural Science Foundation 16ZR1406500,17ZR1405100Shanghai Municipal Natural Science Foundation 19ZR1431800Shanghai Municipal Population and Family Planning Commission 20174Y0042
6 · The paper itself

Abstract

purposeTumor microenvironment is important in the progression of clear cell renal cell carcinoma (ccRCC), and its prognostic value is still unclear. Recent reports demonstrated tumor-infiltrating CD39 EXPERIMENTAL

designWe immunohistochemically evaluated clinical value of CD39

resultsWe found that accumulation of CD39

conclusionsHigh CD39

Indexed as

AdolescentAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsApyraseBiomarkers, TumorCarcinoma, Renal CellCD8-Positive T-LymphocytesFemaleFollow-Up StudiesHumansImmune EvasionKidney NeoplasmsLymphocytes, Tumor-InfiltratingMaleApyraseBiomarkers, TumorENTPD1 protein, humanCD39CD8+ T cellClear cell renal cell carcinomaPrognosisTyrosine kinase inhibitors

Identifiers

PMID32306075
PMCPMC11027701
OpenAlexW3017231491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.