ArticleInternational journal of colorectal disease2020
Prognostic value of serum inflammatory markers in colorectal cancer.
Article in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Systemic Inflammatory Biomarkers as Prognostic Indicators in Metastatic Colorectal Cancer: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Severe postoperative complications after minimally invasive esophagectomy reduce the long-term prognosis of well-immunonutrition patients with locally advanced esophageal squamous cell carcinoma.Annals of medicine · 2025Article
- Hypoalbuminemia, but not derived neutrophil to lymphocyte ratio (dNLR), predicts overall survival in neuroendocrine tumours undergoing peptide receptor radionuclide therapy: A retrospective, cohort study of 557 patients.Journal of neuroendocrinology · 2025Article
- Prognostic Value of Preoperative Albumin-to-Alkaline Phosphatase Ratio for Survival in Colorectal Cancer Patients Undergoing Surgery.Journal of clinical medicine · 2025Article
- Effect of the lymphocyte-to-monocyte ratio on the prognosis of patients with obstructive colorectal cancer with a colonic stent: a retrospective multicenter study in Japan.Surgery today · 2025Article
- Renal dysfunction as a predictor of recurrence and prognosis in colorectal cancer.Frontiers in oncology · 2025Article
- Assessing Frailty in Gastrointestinal Cancer: Two Diseases in One?Current oncology reports · 2024Review
- The Association of Inflammatory Related Markers with the Prognosis in Elderly Patients with Colorectal Cancer.Cancer management and research · 2024Article
- Inflammatory Response Markers as Predictors of Colorectal Cancer Prognosis.Ewha medical journal · 2023Review
- Prediagnostic Prescription Antibiotics Use and Survival in Patients with Colorectal Cancer: A Swedish National Register-Based Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Salvage transoral videolaryngoscopic surgery for post-irradiation recurrence of hypopharyngeal carcinoma.Laryngoscope investigative otolaryngology · 2023Article
- Predictive value of the Naples prognostic score on postoperative outcomes in patients with rectal cancer.Langenbeck's archives of surgery · 2023Article
- Presepsin (soluble CD14 subtype) as a risk factor for the development of infectious and inflammatory complications in operated colorectal cancer patients.Annals of coloproctology · 2022Article
- Glasgow prognostic score and combined positive score for locally advanced rectal cancer.Annals of surgical treatment and research · 2022Article
- Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients.International journal of molecular sciences · 2021Review
- Machine Learning-based Model for Predicting Postoperative Complications among Patients with Colonic Perforation: A Retrospective study.Journal of the anus, rectum and colon · 2021Article
- The Elevated Pre-Treatment C-Reactive Protein Predicts Poor Prognosis in Patients with Locally Advanced Rectal Cancer Treated with Neo-Adjuvant Radiochemotherapy.Diagnostics (Basel, Switzerland) · 2020Article
- A Ten-NFrontiers in oncology · 2020Article
- Novel Model to Predict the Prognosis of Patients with Stage II-III Colon Cancer.BioMed research international · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo date, there have been many studies on postoperative complications and oncologic outcomes, but the findings remain controversial. The purpose of the study was to determine the prognostic value of serum inflammatory markers as pretreatment in curatively resected colorectal cancer. The effects of serum inflammatory marker levels on postoperative morbidity were also examined.
methodsProspectively collected data from 1590 patients with primary sporadic colorectal adenocarcinoma who underwent curative resection between September 2012 and December 2013 at our institution were retrospectively analyzed. White blood cell count (× 10
resultsThe median follow-up period for the 1590 patients was 59 months. The overall postoperative morbidity rate was 24.8%. In multivariate analysis, female sex (P = 0.006), rectal cancer other than colon cancer (P < 0.001), CEA level > 5 ng/ml (P < 0.001), ESR > 27 mm/h (P = 0.014), and a GPS of 1 or 2 (P < 0.001) were independent risk predictors for morbidity. A GPS of 1 or 2 (P < 0.001) and postoperative morbidity (P < 0.001) significantly affected both overall survival and disease-free survival in multivariate analyses.
conclusionsA GPS of 1 or 2 is a significant risk factor for postoperative morbidity and a prognostic factor for long-term survival.
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