Evidence map›Paper›PMID 32306034›Full record

ArticleEuropean heart journal2020

Chronotherapy in hypertension: the devil is in the details.

Greg Guthrie, Neil Poulter, Thomas Macdonald, Ian Ford, Isla Mackenzie, Evelyn Findlay, Bryan Williams, Morris Brown, Chim Lang, David Webb

Open access · greenAbstract readComment
PubMed Publisher
In one paragraph

Article in European heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Evening versus morning dosing regimen drug therapy for hypertension.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Trial
  3. Review
  4. Review
  5. Advances in the Treatment Strategies in Hypertension: Present and Future.Journal of cardiovascular development and disease · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Circadian control of human cardiovascular function.Current opinion in pharmacology · 2021
    Review
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Greg GuthrieMedicines Monitoring Unit & Hypertension Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee DD2 1GZ, UK.
Neil PoulterFaculty of Medicine, School of Public Health, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Thomas MacdonaldMedicines Monitoring Unit & Hypertension Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee DD2 1GZ, UK.
Ian FordRobertson Centre for Biostatistics, University of Glasgow, Boyd Orr Building, Glasgow G12 8QQ, UK.
Isla MackenzieMedicines Monitoring Unit & Hypertension Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee DD2 1GZ, UK.
Evelyn FindlayMedicines Monitoring Unit & Hypertension Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee DD2 1GZ, UK.
Bryan WilliamsInstitute of Cardiovascular Sciences, University College London, Maple House, 149 Tottenham Court Road, London W1T 7DN, UK.
Morris BrownCentre of Clinical Pharmacology, Queen Mary University of London, Mile End Road, London E1 4NS, UK.
Chim LangDivision of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee DD1 4HN, UK.
David WebbCentre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
University of Dundee · GBImperial College London · GBQueen Mary University of London · GBThe Queen's Medical Research Institute · GBUniversity College London · GBUniversity of Glasgow · GB

Funding

Medical Research Council MC_PC_13090
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiovascular DiseasesHypertensionChronotherapyHeart Disease Risk FactorsHumansRisk Factors

Identifiers

PMID32306034
OpenAlexW3016310279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.