SynthesisWorld neurosurgery2020
Spasm Freedom Following Microvascular Decompression for Hemifacial Spasm: Systematic Review and Meta-Analysis.
Synthesis in World neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Which surgical technique has a superior clinical outcome in microvascular decompression? a systematic review and meta-analysis study of transposition versus interposition for trigeminal neuralgia and hemifacial spasm.Neurosurgical review · 2025Pooled it
- Efficacy and safety of reoperation for residual or recurrent hemifacial spasm after microvascular decompression: a systematic review and meta-analysis.Neurosurgical review · 2024Pooled it
- Bibliometric analysis of studies on the treatment of hemifacial spasm.Frontiers in neurology · 2022Pooled it
- Spasm Freedom Following Microvascular Decompression for Hemifacial Spasm: Systematic Review and Meta-Analysis.World neurosurgery · 2020Pooled it
- How I do it: Implant-free transposition technique for microvascular decompression in hemifacial spasm.Acta neurochirurgica · 2026Article
- Hemodynamic Features of Offending Vessels in Primary Hemifacial Spasm: A Computational Fluid Dynamics Study.Annals of biomedical engineering · 2026Article
- Venous compression of the facial nerve root exit zone by a transverse pontine vein: Intraoperative findings and quantitative lateral spread response monitoring.Surgical neurology international · 2026Article
- Electroacupuncture for chemotherapy-induced hemifacial spasm: a case report.Frontiers in medicine · 2026Article
- Hemifacial spasm: an update on pathophysiology, investigations and management.Journal of neurology · 2025Review
- Hemilingual spasm treated with microvascular decompression of the posterior inferior cerebellar artery: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Determining prognostic factors in the treatment of primary hemifacial spasm: Clinical outcomes and complications. A literature review.World neurosurgery: X · 2025Article
- Decompression Surgery in Elderly Patients with Hemifacial Spasm Refractory to Botulinum Toxin.Movement disorders clinical practice · 2024Article
- Radiofrequency thermocoagulation as a treatment for hemifacial spasm: long-term follow-up and management of recurrences.Acta neurochirurgica · 2024Article
- Comparison of transposition and interposition methods in microvascular decompression for hemifacial spasm: an analysis of 109 cases performed by a single surgeon in a single-center retrospective study.Acta neurochirurgica · 2024Article
- Article
- Potential reasons for failure and recurrence in microvascular decompression for hemifacial spasm.Acta neurochirurgica · 2023Article
- Reoperation for residual or recurrent hemifacial spasm after microvascular decompression.Acta neurochirurgica · 2022Article
- Electroacupuncture on Hemifacial Spasm and Temporomandibular Joint Pain Co-Morbidity: A Case Report.Frontiers in neurology · 2022Article
- Review
- Facial root entry/exit zone contact in microvascular decompression for hemifacial spasm: a historical control study.Annals of translational medicine · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundHemifacial spasm (HFS) is a debilitating disorder characterized by intermittent involuntary movement of muscles innervated by the facial nerve. HFS is caused by neurovascular compression along the facial nerve root exit zone and can be treated by microvascular decompression (MVD). The goal was to determine rates and predictors of spasm freedom after MVD for HFS.
methodsA literature search using the key terms "microvascular decompression" and "hemifacial spasm" was performed. The primary outcome variable was spasm freedom at last follow-up. Analysis was completed to evaluate for variables associated with spasm-free outcome.
resultsA total of 39 studies including 6249 patients were analyzed. Overall spasm freedom rate was 90.5% (5652/6249) at a follow-up of 1.25 ± 0.04 years. There was no significant relationship between spasm freedom versus persistent spasm and age at surgery, timing of follow-up, gender, disease duration, side of disease, or vessel type. Spasm freedom was more likely after an initial surgery versus a redo MVD (odds ratio 4.16, 95% confidence interval 1.99-8.68; P < 0.01).
conclusionsMVD works well for HFS with cure rates >90% at 1-year follow-up in 6249 patients from 39 studies. A significant predictor of long-term spasm freedom at 1 year was an initial MVD as compared to repeat MVD. The majority of published manuscripts on MVD for HFS are heterogeneous single-institutional retrospective studies. As such, a large-scale meta-analysis reporting outcome rates and evaluating significant predictors of spasm freedom provides utility in the absence of randomized controlled studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.