Evidence map›Paper›PMID 32305457›Full record

ArticleContemporary clinical trials2020

Translating research into practice: Protocol for a community-engaged, stepped wedge randomized trial to reduce disparities in breast cancer treatment through a regional patient navigation collaborative.

Tracy A Battaglia, Karen M Freund, Jennifer S Haas, Nicole Casanova, Sharon Bak, Howard Cabral, Rachel A Freedman, Karen Burns White, Stephenie C Lemon, TRIP Consortium

Open access · hybridAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Patient navigation programmes for symptomatic lung cancer patients: a scoping review.Archives of public health = Archives belges de sante publique · 2025
    Pooled it
  3. A Systematic Review of Electronic Community Resource Referral Systems.American journal of preventive medicine · 2023
    Pooled it
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  17. Assessment of patient navigation programs for breast cancer patients across the city of Boston.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  18. Cross fertilisation of Public Health and Translational Research.Journal of the Indian Institute of Science · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Tracy A BattagliaWomen's Health Unit, Section of General Internal Medicine, Boston University School of Medicine, Boston, MA, United States of America. Electronic address: Tracy.Battaglia@bmc.org.
Karen M FreundInstitute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, United States of America; Division of Internal Medicine and Primary Care, Department of Medicine, Tufts Medical Center, Boston, MA, United States of America; Tufts University School of Medicine, Boston, MA, United States of America.
Jennifer S HaasDivision of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America.
Nicole CasanovaWomen's Health Unit, Section of General Internal Medicine, Boston University School of Medicine, Boston, MA, United States of America.
Sharon BakWomen's Health Unit, Section of General Internal Medicine, Boston University School of Medicine, Boston, MA, United States of America; Boston University School of Medicine, Boston, MA, United States of America.
Howard CabralDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
Rachel A FreedmanDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, United States of America.
Karen Burns WhiteInitiative to Eliminate Cancer Disparities, Dana Farber/Harvard Cancer Center, Boston, MA, United States of America.
Stephenie C LemonDivision of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.
TRIP Consortium
Boston University · USDana-Farber Cancer Institute · USDana-Farber/Harvard Cancer Center · USMassachusetts General Hospital · USTufts University · USUniversity of Massachusetts Chan Medical School · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Tufts Clinical and Translational Science Institute (Pilot Supplement)UL1TR002544 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2018 to 2022
$50.2M
University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
Harvard Clinical and Translational Science Center (UL1)UL1TR000170 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2012 to 2013
$31.4M
Translating Research Into Practice: A Regional Collaborative to Reduce Disparities in Breast Cancer CareU01TR002070 · NCATS · BOSTON MEDICAL CENTER · PI BATTAGLIA, TRACY ANN, FREUND, KAREN · 2017 to 2021
$8.7M
NCATS NIH HHS U01 TR002070NCATS NIH HHS UL1 TR000170NCATS NIH HHS UL1 TR001430NCATS NIH HHS UL1 TR001453NCATS NIH HHS UL1 TR002541NCATS NIH HHS UL1 TR002544
6 · The paper itself

Abstract

backgroundRacial and socioeconomic disparities in breast cancer mortality persist. In Boston, MA, Black, Non-Hispanic women and Medicaid-insured individuals are 2-3 times more likely to have delays in treatment compared to White or privately insured women. While evidence-based care coordination strategies for reducing delays exist, they are not systematically implemented across healthcare settings.

methodsTranslating Research Into Practice (TRIP) utilizes community engaged research methods to address breast cancer care delivery disparities. Four Massachusetts Clinical and Translational Science Institute (CTSI) hubs collaborated with the Boston Breast Cancer Equity Coalition (The Coalition) to implement an evidence-based care coordination intervention for Boston residents at risk for delays in breast cancer care. The Coalition used a community-driven process to define the problem of care delivery disparities, identify the target population, and develop a rigorous pragmatic approach. We chose a cluster-randomized, stepped-wedge hybrid type I effectiveness-implementation study design. The intervention implements three evidence-based strategies: patient navigation services, a shared patient registry for use across academic medical centers, and a web-based social determinants of health platform to identify and address barriers to care. Primary clinical outcomes include time to first treatment and receipt of guideline-concordant treatment, which are captured through electronic health records abstraction. We will use mixed methods to collect the secondary implementation outcomes of acceptability, adoption/penetration, fidelity, sustainability and cost.

conclusionTRIP utilizes an innovative community-driven research strategy, focused on interdisciplinary collaborations, to design and implement a translational science study that aims to more efficiently integrate proven health services interventions into clinical practice.

Indexed as

Black or African AmericanBreast NeoplasmsHispanic or LatinoInterinstitutional RelationsPatient NavigationAcademic Medical CentersBostonCommunity ParticipationFemaleHealthcare DisparitiesHumansMedicaidMedically UninsuredMulticenter Studies as TopicPragmatic Clinical Trials as TopicProspective StudiesBreast cancer disparitiesImplementation sciencePatient navigationSocial determinants of healthStepped-wedge design

Identifiers

PMID32305457
PMCPMC7884078
OpenAlexW3016590867

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.