ReviewBiological psychiatry. Cognitive neuroscience and neuroimaging2020
Toward a Revised Nosology for Attention-Deficit/Hyperactivity Disorder Heterogeneity.
Review in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 3 syntheses or guidelines pooled it, 123 citations in OpenAlex.
- Pooled it
- Event-related brain oscillations in attention-deficit/hyperactivity disorder (ADHD): A systematic review and meta-analysis.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2022Pooled it
- Adult ADHD and emerging models of maladaptive personality: a meta-analytic review.BMC psychiatry · 2021Pooled it
- A Neuroaffirmative, Self-Determination Theory-Based Psychosocial Intervention for Adults With Attention-Deficit/Hyperactivity Disorder: Randomized Feasibility Study.JMIR formative research · 2025Trial
- Digital Cognitive Training for Children with Attention Deficit Hyperactivity Disorder.Journal of psycholinguistic research · 2023Trial
- The role of single trial variability in event related potentials in children with attention deficit hyperactivity disorder.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Trial
- Methylphenidate, Guanfacine, and Combined Treatment Effects on Electroencephalography Correlates of Spatial Working Memory in Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2023Trial
- Reproducible Temperament Profiles in Adolescents With Attention-Deficit/Hyperactivity Disorder Prospectively Predict Clinical Outcomes.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Interrogating cognitive and neural group variation in childhood: Examples in adolescent brain cognitive development and Oregon attention-deficit/hyperactivity disorder-1000 cohorts.Journal of psychopathology and clinical science · 2026Article
- A Four-Dimensional Model of Attention-Deficit/Hyperactivity Disorder: Toward Improved Recognition of Female ADHD.International journal of molecular sciences · 2026Review
- The conceptual landscape of self-regulation in neurodevelopmental conditions: an overview of reviews.Nature human behaviour · 2026Review
- Executive Function Profiles in ADHD and Dyslexia: A Mixed-Method Neurocognitive Analysis.Neurology international · 2026Article
- Integrating Transdiagnostic and Biopsychosocial Approaches to Move Beyond Categorical Diagnoses in Neurodevelopmental Disorders: A Perspective Review.PsyCh journal · 2026Review
- Attention-Deficit/Hyperactivity Disorder Subtypes Defined by Cognition Have a Distinct Neural and Clinical Profile and Differ in Response to Atomoxetine.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Mapping ADHD Heterogeneity and Biotypes by Topological Deviations in Morphometric Similarity Networks.JAMA psychiatry · 2026Article
- Emotion Dysregulation in Children with ADHD: Irritability is Associated with EEG-Measured Frontal Alpha Asymmetry in Response to Emotional Stimuli.Research on child and adolescent psychopathology · 2026Article
- ADHD as a disorder of operational capacity: a buffered-state framework for sustained engagement instability.Frontiers in psychiatry · 2026Article
- Reactivity and regulation of negative and positive emotions in child- and adolescent diagnostic and trait-level ADHD: a cross-sectional study.BMC psychiatry · 2025Article
- Distinct neuroimaging subtypes of ADHD among adolescents based on semi-supervised learning.Translational psychiatry · 2025Article
- Cognitive Control Decision-Making Dynamics Across Internalizing and Externalizing Symptoms in Youth.Research on child and adolescent psychopathology · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Attention-deficit/hyperactivity disorder (ADHD) is among the many syndromes in the psychiatric nosology for which etiological signal and clinical prediction are weak. Reducing phenotypic and mechanistic heterogeneity should be useful to arrive at stronger etiological and clinical prediction signals. We discuss key conceptual and methodological issues, highlighting the role of dimensional features aligned with Research Domain Criteria and cognitive, personality, and temperament theory as well as neurobiology. We describe several avenues of work in this area, utilizing different statistical, computational, and machine learning approaches to resolve heterogeneity in ADHD. We offer methodological and conceptual recommendations. Methodologically, we propose that an integrated approach utilizing theory and advanced computational logic to address targeted questions, with consideration of developmental context, can render the heterogeneity problem tractable for ADHD. Conceptually, we conclude that the field is on the cusp of justifying an emotionally dysregulated subprofile in ADHD that may be useful for clinical prediction and treatment testing. Cognitive profiles, while more nascent, may be useful for clinical prediction and treatment assignment in different ways depending on developmental stage. Targeting these psychological profiles for neurobiological and etiological study to capture different pathophysiological routes remains a near-term opportunity. Subtypes are likely to be multifactorial, cut across multiple dimensions, and depend on the research or clinical outcomes of interest for their ultimate selection. In this context parallel profiles based on cognition, emotion, and specific neural signatures appear to be on the horizon, each with somewhat different utilities. Efforts to integrate such cross-cutting profiles within a conceptual dysregulation framework are well underway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.