Trial reportJournal of clinical hypertension (Greenwich, Conn.)2020
Validating the Framingham Hypertension Risk Score: A 4-year follow-up from the Brazilian Longitudinal Study of the Adult Health (ELSA-Brasil).
Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Predictive variables and diagnostic performance of cross-sectional models for hypertension detection: a systematic review.Frontiers in cardiovascular medicine · 2025Pooled it
- Prognostic risk models for incident hypertension: A PRISMA systematic review and meta-analysis.PloS one · 2024Pooled it
- Prediction of hypertension using traditional regression and machine learning models: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Validating the Framingham Hypertension Risk Score: A 4-year follow-up from the Brazilian Longitudinal Study of the Adult Health (ELSA-Brasil).Journal of clinical hypertension (Greenwich, Conn.) · 2020Trial
- Development and validation of a hypertension risk prediction model using electronic health records data from general practices in Hampshire and Isle of Wight integrated care system.BMC cardiovascular disorders · 2026Article
- Combinations of physical activity, sedentary behavior and sleep and their associations with cardiovascular risk.BMC public health · 2025Article
- A Novel, Low-Cost Glaucoma Calculator to Identify Glaucoma Patients and Stratify Management.Journal of ophthalmology · 2022Article
- Development and Validation of Decision Rules Models to Stratify Coronary Artery Disease, Diabetes, and Hypertension Risk in Preventive Care: Cohort Study of Returning UK Biobank Participants.Journal of personalized medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Framingham Heart Study published an equation that permits to estimate the 4-year incidence of hypertension among adults. In Brazil, only the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) of 15 105 men and women aged 35-74 years enrolled in 2008-2010 has data that can validate the Framingham Risk Score for Hypertension and create a new equation according to the Brazilian population. We examined the predictive performance of the Framingham Risk Score for Hypertension in the ELSA-Brasil using as an outcome variable, the 4-year incidence of hypertension. We split randomly the 8027 participants who participated in the second visit (2012-2014) and without hypertension at baseline in derivation data set (n = 4825; 60%) and a validation data set (n = 3202 participants; 40%). The area under the curve for Framingham Risk Score for Hypertension and ELSA-Brasil Risk Score was relatively similar. Hosmer-Lemeshow chi-squared statistic applied for the Framingham Risk Score was 3.78 (P-value = .876) and for our model was 8.22 (P-value = .41), disclosing good discrimination and calibration for both models. Even with these classification intervals, our model presents more underestimation of the risk, classifying 15% of the participants with new onset of hypertension in low risk vs 9% of the Framingham model and less overestimation of the risk, classifying 17% of the participants without hypertension as high risk vs 24% of the Framingham model. We concluded that the Framingham Risk Score for Hypertension has an acceptable performance when applied in the ELSA-Brasil population with good discrimination and calibration.
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