Evidence map›Paper›PMID 32304127›Full record

ArticleCancer science2020

CD4

Naoko Imai, Isao Tawara, Makiko Yamane, Daisuke Muraoka, Hiroshi Shiku, Hiroaki Ikeda

Open access · goldAbstract read
In one paragraph

Article in Cancer science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. IL-2 Free Expansion of T Cells with Immunofilaments.Advanced healthcare materials · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Immune profiling identifies CD161Journal of translational medicine · 2025
    Article
  11. Article
  12. Article
  13. CD4Trends in cancer · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Phenotypic and Functional Characterization of Memory CD4Methods in molecular biology (Clifton, N.J.) · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Naoko ImaiDepartment of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Tsu, Japan.
Isao TawaraDepartment of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Japan.
Makiko YamaneDepartment of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Tsu, Japan.
Daisuke MuraokaDepartment of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Tsu, Japan.
Hiroshi ShikuDepartment of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Tsu, Japan.
Hiroaki IkedaDepartment of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Tsu, Japan.ORCID https://orcid.org/0000-0002-8012-4796
Mie University · JP

Funding

Japan Agency for Medical Research and DevelopmentMinistry of Education, Culture, Sports, Science and Technology
6 · The paper itself

Abstract

Polyfunctionality/multifunctionality of effector T cells at the single cell level has been shown as an important parameter to predict the quality of T cell response and immunological control of infectious disease and malignancy. However, the fate of polyfunctional CD8

Indexed as

AnimalsCD4-Positive T-LymphocytesImmunologic MemoryMiceNeoplasmsT-Lymphocytes, Cytotoxiccancer immunotherapyCD4+ T cellCTLIL-2polyfunctionality

Identifiers

PMID32304127
PMCPMC7293103
OpenAlexW3016495142

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.