ArticleMaternal and child health journal2020
Impact of Perinatal Depression and Anxiety on Birth Outcomes: A Retrospective Data Analysis.
Article in Maternal and child health journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 5 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Depression and antidepressant use in pregnancy and adverse maternal and offspring outcomes: a systematic review and meta-analysis.Molecular psychiatry · 2025Pooled it
- Perinatal Mental Health Interventions with a Parent-Child Relational Component: A Systematic Review of the Effects on Mothers and Dyads.Clinical child and family psychology review · 2025Pooled it
- Association between sleep disorders during pregnancy and risk of postpartum depression: a systematic review and meta-analysis.Archives of women's mental health · 2023Pooled it
- The prevalence of borderline personality features and borderline personality disorder during the perinatal period: a systematic review and meta-analysis.Archives of women's mental health · 2022Pooled it
- Can psychological interventions prevent or reduce risk for perinatal anxiety disorders? A systematic review and meta-analysis.General hospital psychiatryPooled it
- The impact of ingestion of Bifidobacterium longum NCC3001 on perinatal anxiety and depressive symptoms: a randomized controlled trial.Scientific reports · 2025Trial
- Validation of the intolerance of uncertainty scale-12 in a sample of pregnant people.BMC pregnancy and childbirth · 2025Trial
- Prenatal anxiety, tobacco use, and infant birth weight: a multilevel analysis of PRAMS data.Archives of women's mental health · 2026Article
- Subtypes and associated factors of prenatal depressive symptoms and their association with health-related quality of life among pregnant women: a cross-sectional study.BMC pregnancy and childbirth · 2026Article
- Article
- Perinatal mood and anxiety diagnoses and treatment increased among medicaid births, 2017-2021.Scientific reports · 2026Article
- Taxonomy of access to mental healthcare for economically marginalized women during a public health crisis: a qualitative study of obstetric professionals and perinatal women during the COVID-19 pandemic.Frontiers in psychiatry · 2026Article
- Real-world evaluation of Chinese National Maternal and Newborn Safety Action Plan for reducing neonatal mortality among pregnant women with conditions: a retrospective, matched, population-based cohort study.BMJ public health · 2026Article
- Efficacy of Gut Microbiome-Targeted Interventions on Mental Health Symptoms in Women Across Key Hormonal Life Stages: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Healthcare (Basel, Switzerland) · 2025Review
- Effectiveness of an immersive virtual reality intervention to reduce anxiety during pregnancy: a quasiexperimental single-group pre-post study.BMC pregnancy and childbirth · 2025Article
- The Association Between Psychosocial Stress and Perinatal Maternal Depressive Symptoms: A Case-Control Study in a Regional Medical Center in Hungary.Journal of personalized medicine · 2025Article
- The Effect of Self-Compassion Distant Education on Depression in Pregnant Women: A Randomized Clinical Trial.Health science reports · 2025Article
- Depression among Latina women in the United States from pregnancy to early postpartum: longitudinal examination of risk factors.BMC pregnancy and childbirth · 2025Article
- The Effects of Online Cognitive Behavioral Therapy on Postpartum Depression: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Anxiety Sensitivity in the Perinatal Period: A Scoping Review.Mental health & prevention · 2025Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesDuring the perinatal period, 10-20% of women experience anxiety and/or depression. Untreated perinatal depression has the potential for adverse effects on the family and infant resulting in long-term deleterious consequences. This study measured the association between self-reported depression using the Edinburgh Postnatal Depression Scale scores, self-reported anxiety and neonatal birth outcomes.
methodsA retrospective design was used with ObstetriX™ data retrieved from 16 metropolitan and rural hospitals in NSW, Australia during 2009-2014. Data were available for 53,646 singleton births. The Edinburgh Postnatal Depression Scale was used to identify self-reported depression while women self-reported pregnancy related anxiety. Regression modelling measured the effects of self-reported depression and self-reported pregnancy related anxiety on neonatal birth outcomes. Linear regression and logistic regression were used to model the effect on birth weight, gestational age, admission to NICU or the SCN, outcome (stillborn vs livebirth), and Apgar scores. Cox proportional hazards regression was used to estimate the effect on neonatal length of stay.
resultsBabies born to women self-reporting anxiety were more likely to have birth complications, be admitted to the nursery, had lower Apgar scores and longer hospital stays. Babies born to women self-identifying as experiencing a level of depression were more likely to have a lower birth weight, shorter gestational age, and, lower Apgar score. These babies were more likely to be admitted to the nursery with an increased length of stay.
conclusionsPerinatal anxiety and depression contribute to poor birth outcomes. Early detection of maternal perinatal anxiety and depression is an important step towards treatment interventions. More research is needed to identify models of care that are effective in identifying and managing perinatal depression and anxiety to improve birth outcomes for women and their babies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.