ReviewInternational journal of clinical oncology2020
Management of gastrointestinal perforation related to radiation.
Review in International journal of clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- Pre-radiotherapy modified prognostic nutritional index predicts acute radiation enteritis in patients with cervical cancer undergoing radiotherapy: A retrospective study.Oncology letters · 2026Article
- An interpretable machine learning model integrating [European journal of nuclear medicine and molecular imaging · 2026Article
- Histotripsy of the hepatic capsule and the gastric wall: acute treatment effects in a swine model.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2025Article
- Delayed Impact of Ionizing Radiation Depends on Sex: Integrative Metagenomics and Metabolomics Analysis of Rodent Colon Content.International journal of molecular sciences · 2025Article
- Proton beam reirradiation for locally recurrent rectal cancer patients with prior pelvic irradiation.Journal of radiation research · 2024Article
- Entero-Cutaneous and Entero-Atmospheric Fistulas: Insights into Management Using Negative Pressure Wound Therapy.Journal of clinical medicine · 2024Review
- Development a risk prediction nomogram for multidrug-resistant bacterial and fungal infection in gastrointestinal fistula patients during the perioperative period.Frontiers in cellular and infection microbiology · 2024Article
- Gastric cancer presenting with ramucirumab-related gastrocolic fistula successfully managed by colonic stenting: a case report.Clinical endoscopy · 2023Article
- Surgical complications of oncological treatments: A narrative review.World journal of gastrointestinal surgery · 2023Review
- Immunomodulation by radiotherapy in tumour control and normal tissue toxicity.Nature reviews. Immunology · 2022Review
- Palliative Radiation Therapy without Chemotherapy for a Patient with Monomorphic Epitheliotropic Intestinal T Cell Lymphoma: A Case Report.Palliative medicine reports · 2022Article
- Efficacy of local salvage therapy for recurrent uterine cervical cancer after definitive radiotherapy.International journal of clinical oncology · 2021Article
- Article
- Bevacizumab-associated events in Japanese women with cervical cancer: a multi-institutional survey of Obstetrical Gynecological Society of Kinki district, Japan.International journal of clinical oncology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Perforation of gastrointestinal (GI) tract is a rare, but serious complication of abdominopelvic irradiation, and it can even occur several years after radiotherapy. As one of the symptoms of radiation enteropathy, it shares common features with other chronic complications and has its own characteristic at the same time. It has been reported that some systematic therapies, such as sorafenib and bevacizumab, could add the risk of radiation-induced GI perforation. The potential mechanisms of aggravated GI injury may be exacerbation of epithelial cell damage, microvascular damage or subsequent inflammatory response. The complicated situation makes it almost impossible to set uniform dose constraints for GI perforation prevention. The majority of cancer patients with GI perforation require emergency surgery, and there is no high quality evidence for supporting the use of any prevention measures. In this review, we summarize the clinical manifestation, risk factors, mechanism, and therapy of radiation-induced GI perforation. A comprehensive treatment plan is crucial to improve the quality of life for cancer survivors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.