Evidence map›Paper›PMID 32303844›Full record

ArticleBrain structure & function2020

Mapping tracts in the human subthalamic area by 11.7T ex vivo diffusion tensor imaging.

Kenichi Oishi, Susumu Mori, Juan C Troncoso, Frederick A Lenz

Open access · greenAbstract read
In one paragraph

Article in Brain structure & function, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Quantification of perforant path fibers for early detection of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Frontiers in neuroanatomy · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kenichi OishiRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 208 Traylor Building, 720 Rutland Ave., Baltimore, MD, 21205, USA. koishi2@jhmi.edu.ORCID http://orcid.org/0000-0002-1200-8611
Susumu MoriRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 208 Traylor Building, 720 Rutland Ave., Baltimore, MD, 21205, USA.
Juan C TroncosoDivision of Neuropathology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Frederick A LenzDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Meyer 8181 Neurosurgery, 600 North Wolfe Street, Baltimore, MD, 21287, USA. flenz1@jhmi.edu.
Johns Hopkins University · USKennedy Krieger Institute · US

Funding

'T V ASSESSMENT - MEMORY DISORDERED PATIENTS'P50AG005146 · NIA · JOHNS HOPKINS UNIVERSITY · PI HUGANIR, RICHARD L · 1985 to 2019
$37.6M
Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI Corinne Pettigrew · 2020 to 2026
$29.3M
Human Networks for Behaviors related to the Expectation of PainR01NS109298 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LENZ, FRED · 2019 to 2023
$3.1M
Behaviors related to Human Neural Activity during Experimental Vigilance to PainR01NS107602 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LENZ, FRED · 2018 to 2022
$3.1M
Multi-Scale Electronic Human Brain AtlasR01NS086888 · NINDS · JOHNS HOPKINS UNIVERSITY · PI MORI, SUSUMU · 2014 to 2018
$1.8M
The Transition from Pain Related Attention to VigilanceR56NS038493 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LENZ, FRED · 2017 to 2017
$555k
NIA NIH HHS P30 AG066507NIA NIH HHS P50 AG005146NIA NIH HHS P50AG05146NINDS NIH HHS R01 NS086888NINDS NIH HHS R01NS086888NINDS NIH HHS R01 NS107602NINDS NIH HHS R01 NS109298NINDS NIH HHS R01NS109298-01NINDS NIH HHS R56 NS038493NINDS NIH HHS RO1 NS096007-01
6 · The paper itself

Abstract

The cortico-basal ganglia-thalamo-cortical feedback loops that consist of distinct white matter pathways are important for understanding in vivo imaging studies of functional and anatomical connectivity, and for localizing subthalamic white matter structures in surgical approaches for movement disorders, such as Parkinson's disease. Connectomic analysis in animals has identified fiber connections between the basal ganglia and thalamus, which pass through the fields of Forel, where other fiber pathways related to motor, sensory, and cognitive functions co-exist. We now report these pathways in the human brain on ex vivo mesoscopic (250 μm) diffusion tensor imaging and on tractography. The locations of the tracts were identified relative to the adjacent gray matter structures, such as the internal and external segments of the globus pallidus; the zona incerta; the subthalamic nucleus; the substantia nigra pars reticulata and compacta; and the thalamus. The connectome atlas of the human subthalamic region may serve as a resource for imaging studies and for neurosurgical planning.

Indexed as

Diffusion Tensor ImagingAdultBasal GangliaHumansImage Processing, Computer-AssistedMaleNeural PathwaysSubthalamic NucleusThalamusWhite MatterBasal gangliaDiffusionFields of ForelSubthalamicThalamusTractography

Identifiers

PMID32303844
PMCPMC7584118
OpenAlexW3016318620

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.