Evidence map›Paper›PMID 32303684›Full record

ArticleCell death & disease2020

The cellular prion protein is a stress protein secreted by renal tubular cells and a urinary marker of kidney injury.

Yohan Bignon, Virginie Poindessous, Hélène Lazareth, Bruno Passet, Jean-Luc Vilotte, Fatima Djouadi, Sophie Mouillet-Richard, Nicolas Pallet

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. The multiple functions of PrPJournal of molecular medicine (Berlin, Germany) · 2022
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yohan Bignon *INSERM U1138, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université de Paris, F-75006, Paris, France.
Virginie Poindessous *INSERM U1138, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université de Paris, F-75006, Paris, France.
Hélène LazarethService de Néphrologie, Hôpital Européen Georges Pompidou, Assistance Publique Hôpitaux de Paris, Paris, France.
Bruno PassetUniversité Paris Saclay, INRAE, AgroparisTech, UMR1313, Génétique animale et biologie intégrative, F78350, Jouy-en-Josas, France.
Jean-Luc VilotteUniversité Paris Saclay, INRAE, AgroparisTech, UMR1313, Génétique animale et biologie intégrative, F78350, Jouy-en-Josas, France.
Fatima DjouadiINSERM U1138, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université de Paris, F-75006, Paris, France.
Sophie Mouillet-RichardINSERM U1138, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université de Paris, F-75006, Paris, France. sophie.mouillet-richard@parisdescartes.fr.ORCID http://orcid.org/0000-0002-8950-1949
Nicolas PalletINSERM U1138, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université de Paris, F-75006, Paris, France. nicolas.pallet@aphp.fr.
Inserm · FRAgroParisTech · FRAssistance Publique – Hôpitaux de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoplasmic Reticulum (ER) stress underlies the pathogenesis of numerous kidney diseases. A better care of patients with kidney disease involves the identification and validation of ER stress biomarkers in the early stages of kidney disease. For the first time to our knowledge, we demonstrate that the prion protein PrP

Indexed as

AnimalsBiomarkersCell ProliferationEndoplasmic Reticulum StressHumansKidneyKidney DiseasesMaleMicePrion ProteinsBiomarkersPrion Proteins

Identifiers

PMID32303684
PMCPMC7165184
OpenAlexW3016339169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.