Evidence map›Paper›PMID 32303656›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Covert sleep-related biological processes are revealed by probabilistic analysis in

Timothy D Wiggin, Patricia R Goodwin, Nathan C Donelson, Chang Liu, Kien Trinh, Subhabrata Sanyal, Leslie C Griffith

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Article
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  7. Active zone plasticity couples sleep need to presynaptic hypophosphorylation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Inferring the genetic basis of sleep states inbioRxiv : the preprint server for biology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Current Evidence for Sleep States inCurrent sleep medicine reports · 2026
    Review
  19. Article
  20. 25 years ofFly · 2025
    Review

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Timothy D WigginDepartment of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02454-9110.ORCID 0000-0003-4432-1626
Patricia R GoodwinDepartment of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02454-9110.
Nathan C DonelsonNeuroscience Discovery, Biogen, Cambridge, MA 02142.
Chang LiuDepartment of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02454-9110.ORCID 0000-0001-6755-4831
Kien TrinhNeuroscience Discovery, Biogen, Cambridge, MA 02142.
Subhabrata SanyalNeuroscience Discovery, Biogen, Cambridge, MA 02142.ORCID 0000-0003-1729-022X
Leslie C GriffithDepartment of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02454-9110; griffith@brandeis.edu.ORCID 0000-0003-3164-9876

Funding

Regulation of Intrinsic Plasticity in Neural CircuitsR01MH067284 · NIMH · BRANDEIS UNIVERSITY · PI GRIFFITH, LESLIE C · 2003 to 2025
$8.8M
Synapses Between Dorsal Paired Medial (DPM) and Dopamine Neurons Modulate Sleep and Learning in DrosophilaF32NS098624 · NINDS · BRANDEIS UNIVERSITY · PI WIGGIN, TIMOTHY DAVID · 2016 to 2017
$113k
NIMH NIH HHS R01 MH067284NINDS NIH HHS F32 NS098624
6 · The paper itself

Abstract

Sleep pressure and sleep depth are key regulators of wake and sleep. Current methods of measuring these parameters in

Indexed as

AnimalsBehavior, AnimalCircadian RhythmDrosophila melanogasterHumansModels, StatisticalMovementSleepWakefulnessarousal thresholdbehaviorHidden Markov Modelhomeostasis

Identifiers

PMID32303656
PMCPMC7211995

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.