Evidence map›Paper›PMID 32303601›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

The Changing Face of Nuclear Cardiology: Guiding Cardiovascular Care Toward Molecular Medicine.

Rudolf A Werner, James T Thackeray, Johanna Diekmann, Desiree Weiberg, Johann Bauersachs, Frank M Bengel

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Molecular imaging of lymphatic organs provides prognostic value after acute myocardial infarction.European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Review
  6. Article
  7. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Unfolding the cardioprotective potential of sigma-1 receptor-directed molecular imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  14. Review
  15. CXCR4-targeted theranostics in oncology.European journal of nuclear medicine and molecular imaging · 2022
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Non-invasive imaging as the cornerstone of cardiovascular precision medicine.European heart journal. Cardiovascular Imaging · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rudolf A WernerDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
James T ThackerayDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Johanna DiekmannDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Desiree WeibergDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and.
Johann BauersachsDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Frank M BengelDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany; and bengel.frank@mh-hannover.de.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radionuclide imaging of myocardial perfusion, function, and viability has been established for decades and remains a robust, evidence-based and broadly available means for clinical workup and therapeutic guidance in ischemic heart disease. Yet, powerful alternative modalities have emerged for this purpose, and their growth has resulted in increasing competition. But the potential of the tracer principle goes beyond the assessment of physiology and function, toward the interrogation of biology and molecular pathways. This is a unique selling point of radionuclide imaging, which has been underrecognized in cardiovascular medicine until recently. Now, molecular imaging methods for the detection of myocardial infiltration, device infection, and cardiovascular inflammation are successfully gaining clinical acceptance. This is further strengthened by the symbiotic quest of cardiac imaging and therapy for an increasing implementation of molecule-targeted procedures, in which specific therapeutic interventions require specific diagnostic guidance toward the most suitable candidates. This review will summarize the current advent of clinical cardiovascular molecular imaging and highlight its transformative contribution to the evolution of cardiovascular therapy beyond mechanical interventions and broad blockbuster medication, toward a future of novel, individualized molecule-targeted and molecular imaging-guided therapies.

Indexed as

CardiologyMolecular MedicineNuclear MedicineCardiovascular DiseasesHumansMolecular Imagingcardiovascular infectioninfiltrative cardiomyopathyinflammationmolecular imagingnuclear cardiology

Identifiers

PMID32303601
PMCPMC7383072
OpenAlexW3016471486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.