Evidence map›Paper›PMID 32303592›Full record

ArticleJournal of virology2020

Human Leukocyte Antigen Susceptibility Map for Severe Acute Respiratory Syndrome Coronavirus 2.

Austin Nguyen, Julianne K David, Sean K Maden, Mary A Wood, Benjamin R Weeder, Abhinav Nellore, Reid F Thompson

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 349 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
349citing papers in PubMed, 2 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

349 citing papers in PubMed, 2 syntheses or guidelines pooled it, 567 citations in OpenAlex.

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289 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Austin NguyenComputational Biology Program, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0001-7940-4830
Julianne K DavidComputational Biology Program, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0003-2690-8239
Sean K MadenComputational Biology Program, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-2212-4894
Mary A WoodComputational Biology Program, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0003-4011-3811
Benjamin R WeederComputational Biology Program, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-4128-5861
Abhinav NelloreComputational Biology Program, Oregon Health & Science University, Portland, Oregon, USA nellore@ohsu.edu thompsre@ohsu.edu.ORCID 0000-0001-8145-1484
Reid F ThompsonComputational Biology Program, Oregon Health & Science University, Portland, Oregon, USA nellore@ohsu.edu thompsre@ohsu.edu.ORCID 0000-0003-3661-5296
Oregon Health & Science University · US

Funding

Quantifying and improving radiotherapy outcomes among VeteransIK2CX002049 · VA · PORTLAND VA MEDICAL CENTER · PI THOMPSON, REID · 2020 to 2025
–
CSRD VA IK2 CX002049
6 · The paper itself

Abstract

Genetic variability across the three major histocompatibility complex (MHC) class I genes (human leukocyte antigen A [HLA-A], -B, and -C genes) may affect susceptibility to and severity of the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19). We performed a comprehensive

Indexed as

Amino Acid SequenceBetacoronavirusClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingEpitopes, T-LymphocyteGenetic VariationGenotypeHaplotypesHistocompatibility Antigens Class IHistocompatibility TestingHumansImmunity, InnatePandemicsPneumonia, ViralEpitopes, T-LymphocyteHistocompatibility Antigens Class IcoronavirusCOVID-19HLAMHC class ISARS-CoV-2

Identifiers

PMID32303592
PMCPMC7307149
OpenAlexW3017304088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.