Evidence map›Paper›PMID 32303567›Full record

ArticleeNeuro

Hypothalamic MCH Neuron Activity Dynamics during Cataplexy of Narcolepsy.

Ying Sun, Meng Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Neural Control of REM Sleep and Motor Atonia: Current Perspectives.Current neurology and neuroscience reports · 2023
    Review
  3. Review
  4. Mapping Network Activity in Sleep.Frontiers in neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ying SunDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425.
Meng LiuDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425 liumen@musc.edu.ORCID 0000-0003-1394-5014
Medical University of South Carolina · US

Funding

Gene Transfer for Cataplexy of NarcolepsyR01NS096151 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LIU, MENG · 2016 to 2020
$2.2M
Cellular Mechanism underlying emotional problems of Alzheimer's diseaseR21AG067445 · NIA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LIU, MENG · 2020 to 2021
$411k
Circuit Mapping for emotion-induced cataplexy of NarcolepsyR21NS101469 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LIU, MENG · 2017 to 2018
$406k
NIA NIH HHS R21 AG067445NINDS NIH HHS R01 NS096151NINDS NIH HHS R21 NS101469
6 · The paper itself

Abstract

Hypothalamic orexin (hypocretin, HCRT) deficiency causes sleep disorder narcolepsy with cataplexy in humans and murine. As another integral group of sleep/wake-regulating neurons in the same brain area, the melanin-concentrating hormone (MCH) neurons' involvement in cataplexy remains ambiguous. Here we used the live animal deep-brain calcium (Ca

Indexed as

CataplexyHypothalamic HormonesNarcolepsyAnimalsHypothalamusMiceNeuronsOrexinsSleep, REMHypothalamic HormonesOrexinscataplexyMCHnarcolepsysleep

Identifiers

PMID32303567
PMCPMC7196720
OpenAlexW3016784968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.