Evidence map›Paper›PMID 32303520›Full record

ArticleCMAJ open

Diabetes-induced eye disease among First Nations people in Ontario: a longitudinal, population-based cohort study.

Robert J Campbell, Roseanne Sutherland, Shahriar Khan, Katharine M Doliszny, Philip L Hooper, Morgan Slater, Eliot Frymire, Baiju R Shah, Jennifer D Walker, Michael E Green

Open access · diamondAbstract readComment
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Monitoring, treatment and control of blood glucose and lipids in Ontario First Nations people with diabetes.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Robert J CampbellDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont. rob.campbell@queensu.ca.
Roseanne SutherlandDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Shahriar KhanDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Katharine M DolisznyDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Philip L HooperDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Morgan SlaterDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Eliot FrymireDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Baiju R ShahDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Jennifer D WalkerDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Michael E GreenDepartment of Ophthalmology (Campbell, Doliszny), Queen's University and Kingston Health Sciences Centre; ICES Queen's (Campbell, Khan, Frymire, Walker, Green), Kingston, Ont.; Chiefs of Ontario (Sutherland), Toronto, Ont.; Department of Ophthalmology (Hooper), Western University and St. Joseph's Hospital, London, Ont.; Department of Family Medicine (Slater, Green) and Health Services and Policy Research Institute (Frymire), Queen's University, Kingston, Ont.; ICES Central (Shah); Department of Medicine (Shah), University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ont.; School of Rural and Northern Health (Walker), Laurentian University, Sudbury, Ont.
Kingston Health Sciences Centre · CAQueen's University · CAQueens University · BD

Funding

CIHR
6 · The paper itself

Abstract

backgroundIn Canada, First Nations populations experience a higher incidence of diabetes and diabetes-related complications than other people. Given the paucity of information on use of preventive eye examinations and the need for interventional care for severe retinopathy among First Nations people, we carried out a population-based study to compare rates of eye examinations and interventional therapies to treat vision-threatening stages of diabetic retinopathy among First Nations people and other people with diabetes in Ontario.

methodsIn collaboration with the Chiefs of Ontario, we carried out a population-based study to identify cohorts of First Nations people and other people with diabetes in Ontario from 1995/96 to 2014/15. We used linked health administrative databases to evaluate rates of eye examination (2005/06-2014/15) and severe diabetic retinopathy treatment and compared them between the 2 populations, and between First Nations people living in and outside of First Nations communities.

resultsWe identified 23 013 First Nations people and 1 364 222 other people diagnosed with diabetes from 1995/96 to 2014/15, of whom 49.8% (95% confidence interval [CI] 48.9%-50.7%) and 53.8% (95% CI 53.7%-54.0%), respectively, received an eye examination in 2014/15. Eye examination rates were similar for First Nations people regardless of whether they lived in or outside a First Nations community. First Nations people developed severe diabetic retinopathy at a faster rate than other people (hazard ratio 1.19, 95% CI 1.02-1.38). The gap between First Nations people and other people in the proportion requiring therapy for severe diabetic retinopathy was especially prominent among younger people. There were no significant differences in rates of diabetic retinopathy treatment in First Nations people stratified by place of residence.

interpretationEye examination rates remain suboptimal among people with diabetes in Ontario and were lower among First Nations people. This is particularly concerning in light of our other findings showing an increased risk of requiring treatment for advanced diabetic retinopathy and the accelerated rate of diabetic retinopathy progression among First Nations people with diabetes.

Identifiers

PMID32303520
PMCPMC7207040
OpenAlexW3017192035

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.