Evidence map›Paper›PMID 32303268›Full record

ReviewMolecular cancer2020

Novel insight into the regulatory roles of diverse RNA modifications: Re-defining the bridge between transcription and translation.

Hanhan Shi, Peiwei Chai, Renbing Jia, Xianqun Fan

Open access · goldAbstract readReview
In one paragraph

Review in Molecular cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed, 2 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 2 syntheses or guidelines pooled it, 252 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. RNA therapeutics: current status and future directions.Signal transduction and targeted therapy · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (mThe Journal of biological chemistry · 2026
    Article
  15. Article
  16. Article
  17. Blood N1-methyladenosine (mCritical care (London, England) · 2026
    Article
  18. Article
  19. Article
  20. Article

104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hanhan ShiDepartment of Ophthalmology, Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 20025, P.R. China.
Peiwei ChaiDepartment of Ophthalmology, Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 20025, P.R. China.
Renbing JiaDepartment of Ophthalmology, Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 20025, P.R. China. renbingjia@sjtu.edu.cn.
Xianqun FanDepartment of Ophthalmology, Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 20025, P.R. China. fanxq@sjtu.edu.cn.
Shanghai Jiao Tong University · CNShanghai Institute of Hematology · CNShanghai Ninth People's Hospital · CN

Funding

UAB Center for Clinical and Translational Science (CCTS)U54TR001005 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2014 to 2014
$4.6M
6 · The paper itself

Abstract

RNA modifications can be added or removed by a variety of enzymes that catalyse the necessary reactions, and these modifications play roles in essential molecular mechanisms. The prevalent modifications on mRNA include N6-methyladenosine (m

Indexed as

Epigenesis, GeneticGene Expression Regulation, NeoplasticProtein BiosynthesisRNA Processing, Post-TranscriptionalAnimalsHumansNeoplasmsRNATranscriptomeRNAdiseasesm1Am5Cm6ARNA modifications

Identifiers

PMID32303268
PMCPMC7164178
OpenAlexW3017326203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.