Evidence map›Paper›PMID 32303181›Full record

ArticleBMC immunology2020

Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells.

Whajung Cho, Jongseon Choe

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

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  11. Systematic analysis of potential targets of the curcumin analog pentagamavunon-1 (PGV-1) in overcoming resistance of glioblastoma cells to bevacizumab.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Whajung ChoResearch Center, Scripps Korea Antibody Institute, Chuncheon, Gangwon, 24341, Republic of Korea.
Jongseon ChoeBIT Medical Convergence Graduate Program and Department of Microbiology and Immunology, School of Medicine, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea. jchoe@kangwon.ac.kr.
Kangwon National University · KRScripps Korea Antibody Institute · KR

Funding

Kangwon National University 520180095Ministry of Education 2019R1A2C1004696
6 · The paper itself

Abstract

backgroundProstaglandin E2 (PGE

resultsFDC-like cells were used to analyze the phosphorylation kinetics of ERK and p38 and the impact of genetic knockdown. PGE

conclusionsOur data indicate that p38 is essentially required for PGE

Indexed as

Cells, CulturedCyclooxygenase 2Dendritic Cells, FollicularDinoprostoneHumansInterleukin-1betaMAP Kinase Signaling Systemp38 Mitogen-Activated Protein KinasesPhosphorylationSignal TransductionCyclooxygenase 2DinoprostoneInterleukin-1betap38 Mitogen-Activated Protein KinasesCyclooxygenaseFollicular dendritic cellMAPKp38Prostaglandin

Identifiers

PMID32303181
PMCPMC7165408
OpenAlexW3016960603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.