ArticleNeuroImage2020
Neuroimaging contrast across the cortical hierarchy is the feature maximally linked to behavior and demographics.
Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Relating Cognition to both Brain Structure and Function: A Systematic Review of Methods.Brain connectivity · 2023Pooled it
- Cardiometabolic health and physical robustness map onto distinct patterns of brain structure and neurotransmitter systems.PLoS biology · 2025Article
- Latent dimension linking functional connectivity with post-stroke deficits across multiple domains.Brain communications · 2025Article
- Multivariate analysis of multimodal brain structure predicts individual differences in risk and intertemporal preference.bioRxiv : the preprint server for biology · 2024Article
- Associations between accelerometer-measured circadian rest-activity rhythm, brain structural and genetic mechanisms, and dementia.Psychiatry and clinical neurosciences · 2024Article
- On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations.Communications biology · 2024Article
- The aging trajectories of brain functional hierarchy and its impact on cognition across the adult lifespan.Frontiers in aging neuroscience · 2024Article
- A cross-cohort replicable and heritable latent dimension linking behaviour to multi-featured brain structure.Communications biology · 2022Article
- Linking interindividual variability in brain structure to behaviour.Nature reviews. Neuroscience · 2022Review
- Gender-Related and Hemispheric Effects in Cortical Thickness-Based Hemispheric Brain Morphological Network.BioMed research international · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
An essential task of neuroscience is to elucidate the relationship between brain activity, brain structure, and human behavior. This study aims to understand this 3-way relationship by studying the population covariance of resting-state functional connectivity, cortical thickness, and behavioral/demographic measures in a large cohort of individuals. Using a data-driven canonical correlation analysis, we found that maximal pairwise correlations between the three modalities are approximately along the same direction across subjects, which is characterized by the change of the overall positive-negative trait of human behavior. More importantly, this behavioral change is associated with a divergent modulation of both resting-state connectivity and cortical thickness across cortical hierarchies between the higher-order cognitive networks and lower-order sensory/motor regions. The findings suggest that the cross-hierarchy contrast of structural and functional brain measures is tightly linked to the overall positive-negative trait of human behavior/demographics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.