Evidence map›Paper›PMID 32302707›Full record

ArticlePharmacological research2020

Could IL-17 represent a new therapeutic target for the treatment and/or management of COVID-19-related respiratory syndrome?

Gian Marco Casillo, Adel Abo Mansour, Federica Raucci, Anella Saviano, Nicola Mascolo, Asif Jilani Iqbal, Francesco Maione

Abstract readLetter
In one paragraph

Article in Pharmacological research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Bridging worlds: a narrative review of IL-17 at the crossroads of inflammation and thrombosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  3. Co-infection withOxford medical case reports · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Interleukin-17A (IL-17A): A silent amplifier of COVID-19.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. The signal pathways and treatment of cytokine storm in COVID-19.Signal transduction and targeted therapy · 2021
    Review
  15. Article
  16. The Novel Coronavirus and Inflammation.Advances in experimental medicine and biology · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Natural history of COVID-19 and current knowledge on treatment therapeutic options.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Gian Marco CasilloImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Adel Abo MansourInstitute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Guraiger, Abha, 62529, Saudi Arabia.
Federica RaucciImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Anella SavianoImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Nicola MascoloImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy.
Asif Jilani IqbalImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy; Institute of Cardiovascular Sciences (ICVS), College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. Electronic address: A.J.Iqbal@bham.ac.uk.
Francesco MaioneImmunoPharmaLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131, Naples, Italy. Electronic address: francesco.maione@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentHumansInterleukin-17PandemicsPneumonia, ViralSARS-CoV-2Interleukin-17

Identifiers

PMID32302707
PMCPMC7194796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.