Evidence map›Paper›PMID 32302412›Full record

ArticleAllergy2020

Two-year drug survival of dupilumab in a large cohort of difficult-to-treat adult atopic dermatitis patients compared to cyclosporine A and methotrexate: Results from the BioDay registry.

Lotte S Spekhorst, Lieneke F M Ariëns, Jorien van der Schaft, Daphne S Bakker, Marijke Kamsteeg, Albert J Oosting, Ilona de Ridder, Annemiek Sloeserwij, Geertruida L E Romeijn, Marlies de Graaf and 4 more

Open access · hybridAbstract readLetter
In one paragraph

Article in Allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Article
  11. From Emollients to Biologicals: Targeting Atopic Dermatitis.International journal of molecular sciences · 2021
    Review
  12. Current Clinical Options for the Management of Itch in Atopic Dermatitis.Clinical, cosmetic and investigational dermatology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Lotte S SpekhorstDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-7537-765X
Lieneke F M AriënsDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0001-5256-0091
Jorien van der SchaftDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.
Daphne S BakkerDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.
Marijke KamsteegDepartment of Dermatology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands.
Albert J OostingDepartment of Dermatology, SpaarneZiekenhuis, Haarlem, The Netherlands.
Ilona de RidderDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.
Annemiek SloeserwijDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.
Geertruida L E RomeijnDepartment of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Marlies de GraafDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.
Inge HaeckDepartment of Dermatology, Reinier de GraafGasthuis, Delft, The Netherlands.
Judith L ThijsDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0003-2753-5235
Marie L A SchuttelaarDepartment of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Marjolein S de Bruin-WellerDepartment of Dermatology and Allergology, National Expertise Center for Atopic Dermatitis, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-1249-6993
Utrecht University · NLUniversity Medical Center Groningen · NLRadboud University Nijmegen · NLReinier de Graaf Hospital · NLSpaarne Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dermatitis, AtopicPharmaceutical PreparationsAdultAntibodies, Monoclonal, HumanizedCyclosporineHumansMethotrexateRegistriesAntibodies, Monoclonal, HumanizedCyclosporinedupilumabMethotrexatePharmaceutical Preparations

Identifiers

PMID32302412
PMCPMC7540274
OpenAlexW3016385680

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.