Evidence map›Paper›PMID 32302379›Full record

ArticleBlood2020

The BTK inhibitor ibrutinib may protect against pulmonary injury in COVID-19-infected patients.

Steven P Treon, Jorge J Castillo, Alan P Skarbnik, Jacob D Soumerai, Irene M Ghobrial, Maria Luisa Guerrera, Kirsten Meid, Guang Yang

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Blood, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 204 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
204citing papers in PubMed, 6 pooled it
36.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

204 citing papers in PubMed, 6 syntheses or guidelines pooled it, 327 citations in OpenAlex.

  1. Pooled it
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  3. Guideline
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  5. Immunomodulation as Treatment for Severe Coronavirus Disease 2019: A Systematic Review of Current Modalities and Future Directions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Pooled it
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  19. [Single-center study of COVID-19 in patients with chronic lymphocytic leukemia].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2024
    Article
  20. Article

144 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Steven P TreonDana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA.
Jorge J CastilloDana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA.
Alan P SkarbnikLymphoproliferative Disorders Program, Novant Health, Charlotte, NC; and.
Jacob D SoumeraiDepartment of Medicine, Harvard Medical School, Boston, MA.
Irene M GhobrialDana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA.
Maria Luisa GuerreraDana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA.
Kirsten MeidDana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA.
Guang YangDana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA.
Brigham and Women's Hospital · USHarvard University · USNovant Health · US

Funding

Trageting the Multiple Myeloma EpigenomeP50CA100707 · NCI · DANA-FARBER CANCER INSTITUTE · PI ANDERSON, KENNETH C. · 2003 to 2023
$45.0M
NCI NIH HHS P50 CA100707
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineAgammaglobulinaemia Tyrosine KinaseAgedBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansLung InjuryMaleMiddle AgedPandemicsPiperidinesPneumonia, ViralProtein Kinase InhibitorsPyrazolesAdenineAgammaglobulinaemia Tyrosine KinaseBTK protein, humanibrutinibPiperidinesProtein Kinase InhibitorsPyrazolesPyrimidines

Identifiers

PMID32302379
PMCPMC7243149
OpenAlexW3016852213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.