Evidence map›Paper›PMID 32302359›Full record

ArticlePloS one2020

Antibiotic use for Australian Aboriginal children in three remote Northern Territory communities.

Timothy Howarth, Raelene Brunette, Tanya Davies, Ross M Andrews, Bhavini K Patel, Steven Tong, Federica Barzi, Therese M Kearns

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Timothy HowarthChild Health, Menzies School of Health Research, Darwin, Northern Territory, Australia.ORCID 0000-0003-3028-0376
Raelene BrunetteChild Health, Sunrise Health Service Aboriginal Corporation, Katherine, Northern Territory, Australia.
Tanya DaviesPublic Health and Planning, Sunrise Health Service Aboriginal Corporation, Katherine, Northern Territory, Australia.
Ross M AndrewsTropical Health, Menzies School of Health Research, Brisbane, Queensland, Australia.
Bhavini K PatelMedicines management-Research, Transformation and Change, Top End Health Service, Darwin, Northern Territory, Australia.
Steven TongDoherty Institute for Infections and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Federica BarziWellbeing and Preventable Chronic Diseases, Menzies School of Health Research, Darwin, Northern Territory, Australia.
Therese M KearnsChild Health, Menzies School of Health Research, Darwin, Northern Territory, Australia.ORCID 0000-0003-0862-7572
Menzies School of Health Research · AUKatherine Hospital · AUNorthern Territory Health Services · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe antibiotic prescription rates for Australian Aboriginal children aged <2 years living in three remote Northern Territory communities.

designA retrospective cohort study using electronic health records.

settingThree primary health care centres located in the Katherine East region.

participantsConsent was obtained from 149 mothers to extract data from 196 child records. There were 124 children born between January 2010 and July 2014 who resided in one of the three chosen communities and had electronic health records for their first two years of life.

main outcome measuresAntibiotic prescription rates, factors associated with antibiotic prescription and factors associated with appropriate antibiotic prescription.

resultsThere were 5,675 Primary Health Care (PHC) encounters for 124 children (median 41, IQR 25.5, 64). Of the 5,675 PHC encounters, 1,542 (27%) recorded at least one infection (total 1,777) and 1,330 (23%) had at least one antibiotic prescription recorded (total 1,468). Children had a median five (IQR 2, 9) prescriptions in both their first and second year of life, with a prescription rate of 5.99/person year (95% CI 5.35, 6.63). Acute otitis media was the most common infection (683 records, 38%) and Amoxycillin was the most commonly prescribed antibiotic (797 prescriptions, 54%). Of the 1,468 recorded prescriptions, 398 (27%) had no infection recorded and 116 (8%) with an infection recorded were not aligned with local treatment guidelines.

conclusionPrescription rates for Australian Aboriginal children in these communities are significantly higher than that reported nationally for non-Aboriginal Australians. Prescriptions predominantly aligned with treatment guidelines in this setting where there is a high burden of infectious disease.

Indexed as

Anti-Bacterial AgentsAustraliaBirth WeightChildFemaleHumansIncidenceInfant, NewbornInfectionsNorthern TerritoryOdds RatioPregnancyPrescriptionsPrimary Health CareAnti-Bacterial Agents

Identifiers

PMID32302359
PMCPMC7164616
OpenAlexW3016296847

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.