ArticleEmerging microbes & infections2020
Jamestown Canyon virus in Massachusetts: clinical case series and vector screening.
Article in Emerging microbes & infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Evolutionary history of Jamestown Canyon virus reveals complex multi-vector ecology.Current biology : CB · 2026Article
- Jamestown Canyon Virus Disease: An Analytic Review of Human Cases Reported from 1982 Through 2022.Viruses · 2026Review
- Evolutionary history of Jamestown Canyon virus disentangles complex multi-vector ecology.bioRxiv : the preprint server for biology · 2026Article
- Jamestown Canyon Virus Seroprevalence in Endemic Regions and Implications for Diagnostic Testing.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Detection of California Serogroup Orthobunyavirus antibodies and Inkoo virus RNA in patients, Finland.Epidemiology and infection · 2025Article
- Powassan Virus Encephalitis in an Immunocompromised Patient: A Diagnostic Challenge With Case Report and Literature Review.Case reports in infectious diseases · 2025Article
- Case Series of Jamestown Canyon Virus Infections with Neurologic Outcomes, Canada, 2011-2016.Emerging infectious diseases · 2024Article
- Surveillance and Genetic Analysis of Jamestown Canyon Virus in New York State: 2001-2022.The American journal of tropical medicine and hygiene · 2023Article
- Jamestown Canyon virus is transmissible by Aedes aegypti and is only moderately blocked by Wolbachia co-infection.PLoS neglected tropical diseases · 2023Article
- Jamestown Canyon virus (Bunyavirales: Peribunyaviridae) vector ecology in a focus of human transmission in New Hampshire, USA.Journal of medical entomology · 2023Article
- Dynamics of eastern equine encephalitis virus during the 2019 outbreak in the Northeast United States.Current biology : CB · 2023Article
- Dynamics of Eastern equine encephalitis virus during the 2019 outbreak in the Northeast United States.medRxiv : the preprint server for health sciences · 2023Article
- Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States.Parasites & vectors · 2022Article
- Laboratory Validation of a Real-Time RT-PCR Assay for the Detection of Jamestown Canyon Virus.Pathogens (Basel, Switzerland) · 2022Article
- Encephalitis Caused by Jamestown Canyon Virus in a Liver Transplant Patient, North Carolina, USA, 2017.Open forum infectious diseases · 2022Article
- Jamestown Canyon Virus (JCV) Encephalitis Mimicking Acute Stroke in Michigan: A Case Report and Review of the Literature.The Neurohospitalist · 2022Article
- Jamestown Canyon virus-mediated meningoencephalitis with unusual laboratory findings.BMJ case reports · 2021Article
- Fatal Case of Chronic Jamestown Canyon Virus Encephalitis Diagnosed by Metagenomic Sequencing in Patient Receiving Rituximab.Emerging infectious diseases · 2021Article
- Diagnostic Approach for Arboviral Infections in the United States.Journal of clinical microbiology · 2020Review
- Emerging orthobunyaviruses associated with CNS disease.PLoS neglected tropical diseases · 2020Review
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 3 countries.
Funding
Abstract
Jamestown Canyon virus (JCV) is a neuroinvasive arbovirus that is found throughout North America and increasingly recognized as a public health concern. From 2004 to 2012, an average of 1.7 confirmed cases were reported annually in the United States, whereas from 2013 to 2018 this figure increased over seventeen-fold to 29.2 cases per year. The rising number of reported human infections highlights the need for better understanding of the clinical manifestations and epidemiology of JCV. Here, we describe nine patients diagnosed with neuroinvasive JCV infection in Massachusetts from 2013, the year of the first reported case in the state, to 2017. Because current diagnostic testing relies on serology, which is complicated by cross-reactivity with related orthobunyaviruses and can be negative in immunosuppressed patients, we developed and evaluated an RT-qPCR assay for detection of JCV RNA. We tested this on the available archived serum from two patients, but did not detect viral RNA. JCV is transmitted by multiple mosquito species and its primary vector in Massachusetts is unknown, so we additionally applied the RT-qPCR assay and confirmatory RNA sequencing to assess JCV prevalence in a vector candidate,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.